CLUH - clustered mitochondria homolog Gene

Also Known as CLU1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 23277

About CLUH

Cytogenetic location: 17p13.3 Genomic coordinates (GRCh38): 17:2,689,387-2,712,020 (from NCBI)

This gene has 15 transcripts (splice variants) and 254 orthologues. Ubiquitous expression in kidney (RPKM 25.8), duodenum (RPKM 18.1) and 25 other tissues.

Summary

Enables mRNA binding activity. Involved in intracellular distribution of mitochondria. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

CLUH Products (3)

mRNA Protein Name
NM_001366661.1 NP_001353590.1 clustered mitochondria protein homolog isoform 1
NM_001366662.1 NP_001353591.1 clustered mitochondria protein homolog isoform 3
NM_015229.4 NP_056044.4 clustered mitochondria protein homolog isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables mRNA binding IDA
IDA: Inferred from direct assay
25349259 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
28514442 GOA
Biological Process GO Annotation Evidence References Source
involved in intracellular distribution of mitochondria IMP
IMP: Inferred from mutant phenotype
25349259 GOA
involved in mitochondrion organization IMP
IMP: Inferred from mutant phenotype
25349259 GOA
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
25349259 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CLUH Protein Structure

CLU_N

CLU_N: Mitochondrial function, CLU-N-term (64 - 139)

CLU

CLU: Clustered mitochondria (356 - 577)

eIF3_p135

eIF3_p135: Translation initiation factor eIF3 subunit 135 (764 - 949)

TPR_10

TPR_10: Tetratricopeptide repeat (1019 - 1060)

TPR_12

TPR_12: Tetratricopeptide repeat (1100 - 1177)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1309 a.a.
Protein Preferred Names Protein Names

clustered mitochondria protein homolog

  • clustered mitochondria (cluA/CLU1) homolog

Related Diseases

Diseases Alias
Fish Allergy

  • Allergy To Fish
Dyschromatosis Universalis Hereditaria

  • Duh
Atrophic Rhinitis

  • Rhinitis, Atrophic

  • Ozena

  • Rhinitis Sicca

  • Dry Rhinitis

  • Ozaena
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02850 CLUH Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus CLUH VGNC VGNC:60988
Rattus norvegicus CLUH RGD RGD:1307222
Bos taurus CLUH VGNC VGNC:50138
Canis familiaris CLUH VGNC VGNC:54935
Macaca mulatta CLUH VGNC VGNC:71370
Mus musculus CLUH MGD MGI:1921398
Others CLUH NCBI