Mypop - Myb-related transcription factor, partner of profilin Gene

Mus musculus

Also known as P42pop; Myodysa

Gene ID: 232934 | Gene type: protein coding

About Mypop

Summary

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and identical protein binding activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including central nervous system; genitourinary system; liver; lung; and spleen. Orthologous to human MYPOP (Myb related transcription factor, partner of profilin). [provided by Alliance of Genome Resources, Apr 2022]

Mypop Products(1)

mRNA	Protein	Name
NM_145579.3	NP_663554.1	myb-related transcription factor, partner of profilin

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables DNA binding	IDA IDA: Inferred from direct assay	15615774	MGI
enables DNA-binding transcription factor activity	IDA IDA: Inferred from direct assay	15615774	MGI
enables DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA IDA: Inferred from direct assay	15615774	MGI
enables DNA-binding transcription repressor activity, RNA polymerase II-specific	IMP IMP: Inferred from mutant phenotype	15615774	MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA IDA: Inferred from direct assay	15615774	MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IMP IMP: Inferred from mutant phenotype	15615774	MGI
enables identical protein binding	IPI IPI: Inferred from physical interaction	15615774	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	15615774	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within negative regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	15615774	MGI
involved in negative regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	15615774	MGI
acts upstream of or within regulation of transcription by RNA polymerase II	IGI IGI: Inferred from genetic interaction	15615774	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in nucleus	IDA IDA: Inferred from direct assay	15615774	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

myb-related transcription factor, partner of profilin

Myb protein P42POP	myb-related protein p42POP
myotonic dystrophy region	partner of profilin

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08968	MYPOP Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS08901	MYH2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Mypop	NCBI	NCBI:339344

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