Ipo7 - importin 7 Gene

Also Known as Imp7; Ranbp7; C330016G14; A330055O14Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 233726

Summary

Enables histone binding activity. Acts upstream of or within innate immune response and protein import into nucleus. Predicted to be located in nucleoplasm. Predicted to be active in cytosol and nuclear envelope. Orthologous to human IPO7 (importin 7). [provided by Alliance of Genome Resources, Apr 2022]

Ipo7 Products (2)

mRNA Protein Name
NM_001362172.2 NP_001349101.1 importin-7 isoform 2
NM_181517.5 NP_852658.2 importin-7 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables histone binding IDA
IDA: Inferred from direct assay
11493596 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
10891500 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within innate immune response IMP
IMP: Inferred from mutant phenotype
19805818 MGI
involved in negative regulation of osteoblast differentiation IMP
IMP: Inferred from mutant phenotype
35922041 MGI
involved in positive regulation of odontoblast differentiation IMP
IMP: Inferred from mutant phenotype
35922041 MGI
involved in positive regulation of protein localization to nucleus IDA
IDA: Inferred from direct assay
35922041 MGI
involved in positive regulation of protein localization to nucleus IMP
IMP: Inferred from mutant phenotype
33548622 MGI
acts upstream of or within protein import into nucleus IDA
IDA: Inferred from direct assay
11493596 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
34995814 MGI
located in nucleus IDA
IDA: Inferred from direct assay
34995814 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

importin-7

  • RAN binding protein 7

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06870 IPO7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ipo7 NCBI NCBI:10527