Ipo7 - importin 7 Gene

Mus musculus

Also known as Imp7; Ranbp7; C330016G14; A330055O14Rik

Gene ID: 233726 | Gene type: protein coding

About Ipo7

Summary

Enables histone binding activity. Acts upstream of or within innate immune response and protein import into nucleus. Predicted to be located in nucleoplasm. Predicted to be active in cytosol and nuclear envelope. Orthologous to human IPO7 (importin 7). [provided by Alliance of Genome Resources, Apr 2022]

Ipo7 Products(2)

mRNA	Protein	Name
NM_001362172.2	NP_001349101.1	importin-7 isoform 2
NM_181517.5	NP_852658.2	importin-7 isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables histone binding	IDA IDA: Inferred from direct assay	11493596	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	10891500	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within innate immune response	IMP IMP: Inferred from mutant phenotype	19805818	MGI
involved in negative regulation of osteoblast differentiation	IMP IMP: Inferred from mutant phenotype	35922041	MGI
involved in positive regulation of odontoblast differentiation	IMP IMP: Inferred from mutant phenotype	35922041	MGI
involved in positive regulation of protein localization to nucleus	IDA IDA: Inferred from direct assay	35922041	MGI
involved in positive regulation of protein localization to nucleus	IMP IMP: Inferred from mutant phenotype	33548622	MGI
acts upstream of or within protein import into nucleus	IDA IDA: Inferred from direct assay	11493596	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	34995814	MGI
located in nucleus	IDA IDA: Inferred from direct assay	34995814	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

importin-7

RAN binding protein 7

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06870	IPO7 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ipo7	NCBI	NCBI:10527

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