Ppfia1 - protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 Gene

Also Known as LIP1; LIP.1; C030014K08Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 233977

Summary

Acts upstream of or within negative regulation of stress fiber assembly. Predicted to be located in several cellular components, including axon; dendrite; and focal adhesion. Predicted to be part of protein-containing complex. Predicted to be active in presynaptic active zone. Is expressed in several structures, including blood vessel endothelium; central nervous system; genitourinary system; retina; and spleen. Orthologous to human PPFIA1 (PTPRF interacting protein alpha 1). [provided by Alliance of Genome Resources, Apr 2022]

Ppfia1 Products (2)

mRNA Protein Name
NM_001033319.2 NP_001028491.1 liprin-alpha-1 isoform B
NM_001195086.1 NP_001182015.1 liprin-alpha-1 isoform A

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16186258 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of stress fiber assembly IDA
IDA: Inferred from direct assay
22266902 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

liprin-alpha-1

  • Liprin-alpha1

  • liprin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10939 PPFIA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ppfia1 NCBI NCBI:8500