PPWD1 - peptidylprolyl isomerase domain and WD repeat containing 1 Gene

Homo sapiens

Gene ID: 23398 | Gene type: protein coding

About PPWD1

Cytogenetic location: 5q12.3 Genomic coordinates (GRCh38): 5:65,563,296-65,587,549 (from NCBI)

This gene has 15 transcripts (splice variants), 196 orthologues and 22 paralogues. Ubiquitous expression in lymph node (RPKM 13.9), appendix (RPKM 11.8) and 25 other tissues.

Summary

Enables cyclosporin A binding activity and peptidyl-prolyl cis-trans isomerase activity. Involved in protein peptidyl-prolyl isomerization. Located in nuclear body. Part of catalytic step 2 spliceosome. [provided by Alliance of Genome Resources, Apr 2022]

PPWD1 Products(4)

mRNA	Protein	Name
NM_001278926.2	NP_001265855.1	peptidylprolyl isomerase domain and WD repeat-containing protein 1 isoform 2
NM_001278927.2	NP_001265856.1	peptidylprolyl isomerase domain and WD repeat-containing protein 1 isoform 3
NM_001278929.2	NP_001265858.1	peptidylprolyl isomerase domain and WD repeat-containing protein 1 isoform 4
NM_015342.4	NP_056157.1	peptidylprolyl isomerase domain and WD repeat-containing protein 1 isoform 1

PPWD1 Protein Structure

WD40

Pro_isomerase

0
100
200
300
400
500
600
646 a.a.

Protein Preferred Names

Protein Names

peptidylprolyl isomerase domain and WD repeat-containing protein 1

epididymis secretory sperm binding protein

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11041	PPWD1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	PPWD1	RGD	RGD:1310204
Bos taurus	PPWD1	VGNC	VGNC:33279
Mus musculus	PPWD1	MGD	MGI:2443069
Canis familiaris	PPWD1	VGNC	VGNC:44932
Felis catus	PPWD1	VGNC	VGNC:64337
Macaca mulatta	PPWD1	VGNC	VGNC:76339

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