FRAT2 - FRAT regulator of WNT signaling pathway 2 Gene
Also Known as FRAT-2
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 23401
About FRAT2
Cytogenetic location: 10q24.1
Genomic coordinates (GRCh38): 10:97,332,497-97,334,729 (from NCBI)
This gene has 1 transcript (splice variant), 61 orthologues and 1 paralogue.
Summary
The protein encoded by this intronless gene belongs to the GSK-3-binding protein family. Studies show that this protein plays a role as a positive regulator of the Wnt signaling pathway. It may be upregulated in tumor progression. [provided by RefSeq, Jul 2008]
FRAT2 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_012083.3 | NP_036215.1 | GSK-3-binding protein FRAT2 |
FRAT2 Protein Structure
GSK-3_bind
GSK-3_bind: Glycogen synthase kinase-3 binding (1 - 214)
- 0
- 100
- 200
- 233 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
GSK-3-binding protein FRAT2 |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Heinz Body Anemias |
|
|
| Nanophthalmos |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(1)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS05091 | FRAT2 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Mus musculus | FRAT2 | MGD | MGI:2673967 |
| Bos taurus | FRAT2 | VGNC | VGNC:55952 |
| Macaca mulatta | FRAT2 | VGNC | VGNC:72727 |
| Rattus norvegicus | FRAT2 | RGD | RGD:1591882 |
| Others | FRAT2 | NCBI |
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