NOMO1 - NODAL modulator 1 Gene

Homo sapiens

Also known as PM5; Nomo

Gene ID: 23420 | Gene type: protein coding

About NOMO1

Cytogenetic location: 16p13.11 Genomic coordinates (GRCh38): 16:14,833,721-14,896,157 (from NCBI)

This gene has 6 transcripts (splice variants), 1 gene allele, 201 orthologues and 2 paralogues. Ubiquitous expression in brain (RPKM 58.5), heart (RPKM 50.3) and 25 other tissues.

Summary

This gene encodes a protein originally thought to be related to the collagenase gene family. This gene is one of three highly similar genes in a region of duplication located on the p arm of chromosome 16. These three genes encode closely related proteins that may have the same function. The protein encoded by one of these genes has been identified as part of a protein complex that participates in the Nodal signaling pathway during vertebrate development. Mutations in ABCC6, which is located nearby, rather than mutations in this gene are associated with pseudoxanthoma elasticum (PXE). [provided by RefSeq, Jul 2008]

NOMO1 Products(1)

mRNA	Protein	Name
NM_014287.4	NP_055102.3	nodal modulator 1 precursor

NOMO1 Protein Structure

CarboxypepD_reg

0
200
400
600
800
1000
1222 a.a.

Protein Preferred Names

Protein Names

nodal modulator 1

nodal modulator 3

Related Diseases

Diseases

Alias

Pseudoxanthoma Elasticum

PXE	Gronblad-Strandberg Syndrome
Pseudoxanthoma Elasticum, Modifier Of Severity Of	Gronblad-Strandberg-Touraine Syndrome
Gronblad Strandberg Syndrome	Groenblad-Strandberg Syndrome
Nevus Elasticus	Pxe - [Pseudoxanthoma Elasticum]

Supraglottis Cancer

Malignant Tumor Of Supraglottis	Supraglottis
Ca Larynx - Supraglottis	Malignant Neoplasm Of Extrinsic Larynx
Malignant Neoplasm Of Supraglottis	Malignant Supraglottic Tumor
Neoplasm Of Supraglottis

Superficial Urinary Bladder Cancer

Superficial Urinary Bladder Carcinoma

Carcinoma Of Urinary Bladder, Superficial

Ulcerative Stomatitis

Stomatitis Ulcerative	Aphthous Stomatitis
Minor Oral Aphthous Ulceration

Noma

Cancrum Oris	Gangrenous Stomatitis
Oro-Facial Gangrene	Noma Neonatorum
Oral Gangrene	Oro-Facial Noma
Stomatitis Gangrenosa	Stomatonecrosis
Gangrene Stomatitis

Bladder Squamous Cell Carcinoma

Squamous Cell Carcinoma Of Bladder	Epidermoid Carcinoma Of The Urinary Bladder
Carcinoma Squamous Cell Bladder

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09422	NOMO1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	NOMO1	MGD	MGI:2385850

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