Psd3 - pleckstrin and Sec7 domain containing 3 Gene

Also Known as EFA6D; D430018P08; 4931420C21Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 234353

Summary

Enables guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of ARF protein signal transduction. Predicted to act upstream of or within ARF protein signal transduction. Located in ruffle membrane. Is expressed in several structures, including brain; eye; genitourinary system; hemolymphoid system gland; and liver. Orthologous to human PSD3 (pleckstrin and Sec7 domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]

Psd3 Products (3)

mRNA Protein Name
NM_027626.1 NP_081902.1 PH and SEC7 domain-containing protein 3 isoform 3
NM_030263.5 NP_084539.2 PH and SEC7 domain-containing protein 3 isoform 1
NM_177698.5 NP_808366.2 PH and SEC7 domain-containing protein 3 isoform 2

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables guanyl-nucleotide exchange factor activity IDA
IDA: Inferred from direct assay
16707115 MGI
Cellular Component GO Annotation Evidence References Source
NOT located in cleavage furrow IDA
IDA: Inferred from direct assay
23603394 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
27241101 MGI
is active in glutamatergic synapse IEP
IEP: Inferred from expression pattern
27241101 MGI
located in membrane IDA
IDA: Inferred from direct assay
16707115 MGI
is active in postsynapse IDA
IDA: Inferred from direct assay
27241101 MGI
is active in postsynapse IEP
IEP: Inferred from expression pattern
27241101 MGI
located in ruffle membrane IDA
IDA: Inferred from direct assay
23603394 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

PH and SEC7 domain-containing protein 3

  • exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 D

  • exchange factor for ARF6 D

  • guanine nucleotide exchange factor for ADP ribosylation factor 6

  • pleckstrin homology and SEC7 domain-containing protein 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS22750 Psmd3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-178737S 1,2-Dilinoleoyl-sn-glycero-3-phospho-L-serine-d3 ammonium / Unkown
HY-178754S 12-Dipalmitoyl-sn-glycero-3-PS-d3 ammonium / Unkown
HY-RS11274 PSD3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Psd3 NCBI NCBI:23362