Kank2 - KN motif and ankyrin repeat domains 2 Gene

Also Known as Ankrd25

Species: Mus musculus

Gene Type: protein coding
Gene ID: 235041

Summary

Involved in glomerular visceral epithelial cell migration and regulation of Rho protein signal transduction. Predicted to be located in mitochondrion. Predicted to be active in cytoplasm. Is expressed in 2nd branchial arch; inner cell mass; limb; limb mesenchyme; and trophectoderm. Human ortholog(s) of this gene implicated in nephrotic syndrome type 16. Orthologous to human KANK2 (KN motif and ankyrin repeat domains 2). [provided by Alliance of Genome Resources, Apr 2022]

Kank2 Products (1)

mRNA Protein Name
NM_145611.4 NP_663586.3 KN motif and ankyrin repeat domain-containing protein 2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in podocyte cell migration IMP
IMP: Inferred from mutant phenotype
25961457 MGI
involved in regulation of Rho protein signal transduction IMP
IMP: Inferred from mutant phenotype
25961457 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

KN motif and ankyrin repeat domain-containing protein 2

  • ankyrin repeat domain 25

  • ankyrin repeat domain-containing protein 25

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07064 KANK2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kank2 NCBI NCBI:25959