2. Gene
  3. Kank2 - KN motif and ankyrin repeat domains 2 Gene

Kank2 - KN motif and ankyrin repeat domains 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Ankrd25

Gene ID: 235041 | Gene type: protein coding

About Kank2

Summary

Involved in glomerular visceral epithelial cell migration and regulation of Rho protein signal transduction. Predicted to be located in mitochondrion. Predicted to be active in cytoplasm. Is expressed in 2nd branchial arch; inner cell mass; limb; limb mesenchyme; and trophectoderm. Human ortholog(s) of this gene implicated in nephrotic syndrome type 16. Orthologous to human KANK2 (KN motif and ankyrin repeat domains 2). [provided by Alliance of Genome Resources, Apr 2022]

Kank2 Products(1)

mRNA Protein Name
NM_145611.4 NP_663586.3 KN motif and ankyrin repeat domain-containing protein 2
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in podocyte cell migration IMP
IMP: Inferred from mutant phenotype
25961457 MGI
involved in regulation of Rho protein signal transduction IMP
IMP: Inferred from mutant phenotype
25961457 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

KN motif and ankyrin repeat domain-containing protein 2

ankyrin repeat domain 25

ankyrin repeat domain-containing protein 25

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07064 KANK2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kank2 NCBI NCBI:25959