Gramd1b - GRAM domain containing 1B Gene

Also Known as mKIAA1201; 3222402H23; A930008A22Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 235283

Summary

Enables Cholesterol binding activity; Cholesterol transfer activity; and phospholipid binding activity. Involved in cellular response to Cholesterol and Cholesterol homeostasis. Located in endoplasmic reticulum membrane; endoplasmic reticulum-plasma membrane contact site; and plasma membrane. Is expressed in several structures, including adrenal medulla; retina; and testis. Orthologous to human GRAMD1B (GRAM domain containing 1B). [provided by Alliance of Genome Resources, Apr 2022]

Gramd1b Products (8)

mRNA Protein Name
NM_001357617.1 NP_001344546.1 protein Aster-B isoform 2
NM_001357618.1 NP_001344547.1 protein Aster-B isoform 3
NM_001357619.1 NP_001344548.1 protein Aster-B isoform 4
NM_001357620.1 NP_001344549.1 protein Aster-B isoform 5
NM_001357621.1 NP_001344550.1 protein Aster-B isoform 6
NM_001357622.1 NP_001344551.1 protein Aster-B isoform 7
NM_001357623.1 NP_001344552.1 protein Aster-B isoform 8
NM_172768.2 NP_766356.1 protein Aster-B isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables cholesterol binding IDA
IDA: Inferred from direct assay
30220461 MGI
enables cholesterol transfer activity IMP
IMP: Inferred from mutant phenotype
30220461 MGI
enables phosphatidic acid binding IDA
IDA: Inferred from direct assay
30220461 MGI
enables phosphatidylserine binding IDA
IDA: Inferred from direct assay
30220461 MGI
Biological Process GO Annotation Evidence References Source
involved in cellular response to cholesterol IDA
IDA: Inferred from direct assay
30220461 MGI
involved in cholesterol homeostasis IMP
IMP: Inferred from mutant phenotype
30220461 MGI
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
30220461 MGI
located in endoplasmic reticulum-plasma membrane contact site IDA
IDA: Inferred from direct assay
30220461 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
30220461 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein Aster-B

  • GRAM domain-containing protein 1B

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05773 GRAMD1B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gramd1b NCBI NCBI:57476