2. Gene
  3. C1qtnf5 - C1q and tumor necrosis factor related protein 5 Gene

C1qtnf5 - C1q and tumor necrosis factor related protein 5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Adie; Mfrp; Ctrp5

Gene ID: 235312 | Gene type: protein coding

About C1qtnf5

Summary

The protein encoded by this gene is a member of the C1q/tumor necrosis factor superfamily. This family member is a secretory protein that functions in eye development. Mutations in this gene are thought to underlie the pathophysiology of late-onset retinal degeneration (L-ORD) and early-onset long anterior zonules (LAZ). Bicistronic transcripts composed of the coding sequences for this gene (C1qtnf5) and the membrane-type frizzled-related protein gene (Mfrp) have been identified, and the resulting products can interact with each Other. Co-transcription of C1qtnf5 and Mfrp has been observed in both human and mouse. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]

C1qtnf5 Products(5)

mRNA Protein Name
NM_001040631.2 NP_001035721.1 complement C1q tumor necrosis factor-related protein 5 precursor
NM_001040632.2 NP_001035722.1 complement C1q tumor necrosis factor-related protein 5 precursor
NM_001190313.1 NP_001177242.1 complement C1q tumor necrosis factor-related protein 5 precursor
NM_001190319.1 NP_001177248.1 complement C1q tumor necrosis factor-related protein 5 precursor
NM_145613.4 NP_663588.2 complement C1q tumor necrosis factor-related protein 5 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables identical protein binding IDA
IDA: Inferred from direct assay
17122142 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
16600989 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within inner ear development IDA
IDA: Inferred from direct assay
21795542 MGI
acts upstream of or within protein secretion IMP
IMP: Inferred from mutant phenotype
17122142 MGI
Cellular Component GO Annotation Evidence Reference Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
17122142 MGI
located in bicellular tight junction IDA
IDA: Inferred from direct assay
17122142 MGI
located in cell projection IDA
IDA: Inferred from direct assay
17122142 MGI
located in extracellular region IDA
IDA: Inferred from direct assay
17122142 MGI
located in extracellular space IDA
IDA: Inferred from direct assay
18783346 MGI
located in lateral plasma membrane IDA
IDA: Inferred from direct assay
17122142 MGI
located in membrane IDA
IDA: Inferred from direct assay
17122142 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
17122142 MGI
part of protein-containing complex IDA
IDA: Inferred from direct assay
18783346 MGI
located in transport vesicle IDA
IDA: Inferred from direct assay
17122142 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

complement C1q tumor necrosis factor-related protein 5

Membrane frizzled-related protein

adiponectin e

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01731 C1QTNF5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens C1qtnf5 NCBI NCBI:114902