Gldn - gliomedin Gene

Also Known as Clom; Colm; Crgl2; Crlg2; CRG-L2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 235379

Summary

Enables protein binding activity involved in heterotypic cell-cell adhesion. Acts upstream of or within clustering of voltage-gated sodium channels; heterotypic cell-cell adhesion; and microvillus organization. Located in extracellular space and plasma membrane. Is expressed in several structures, including genitourinary system; heart; lung; skeletal muscle; and spleen. Human ortholog(s) of this gene implicated in lethal congenital contracture syndrome. Orthologous to human GLDN (gliomedin). [provided by Alliance of Genome Resources, Apr 2022]

Gldn Products (1)

mRNA Protein Name
NM_177350.5 NP_796324.1 gliomedin

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
23897819 MGI
enables protein binding involved in heterotypic cell-cell adhesion IGI
IGI: Inferred from genetic interaction
20188654 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within clustering of voltage-gated sodium channels IMP
IMP: Inferred from mutant phenotype
20188654 MGI
acts upstream of or within microvillus organization IMP
IMP: Inferred from mutant phenotype
20188654 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
17293346 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
17293346 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

gliomedin

  • cancer related gene - liver 2

  • cancer-related gene liver 2 protein

  • collomin

  • olfactomedin-related protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05469 GLDN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22186 Gldn Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28708 Gldn Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gldn NCBI NCBI:342035