Dmxl2 - Dmx-like 2 Gene

Also Known as mKIAA0856; 6330586A12; 6430411K14Rik; E130119P06Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 235380

Summary

Predicted to enable small GTPase binding activity. Acts upstream of or within several processes, including glucose homeostasis; sensory perception of smell; and spermatogenesis. Is active in neuronal dense core vesicle. Is expressed in central nervous system; ganglia; and olfactory epithelium. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 71 and developmental and epileptic encephalopathy 81. Orthologous to human DMXL2 (Dmx like 2). [provided by Alliance of Genome Resources, Apr 2022]

Dmxl2 Products (2)

mRNA Protein Name
NM_172771.2 NP_766359.2 dmX-like protein 2
NM_172771.2 NP_766359.2 dmX-like protein 2

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within brain development IMP
IMP: Inferred from mutant phenotype
29078390 MGI
acts upstream of or within chemical synaptic transmission IMP
IMP: Inferred from mutant phenotype
30735494 MGI
acts upstream of or within corpus callosum development IMP
IMP: Inferred from mutant phenotype
29078390 MGI
acts upstream of or within glucose homeostasis IMP
IMP: Inferred from mutant phenotype
30735494 MGI
acts upstream of sensory perception of smell IMP
IMP: Inferred from mutant phenotype
30735494 MGI
acts upstream of or within sensory perception of smell IMP
IMP: Inferred from mutant phenotype
30735494 MGI
acts upstream of or within spermatogenesis IMP
IMP: Inferred from mutant phenotype
30735494 MGI
Cellular Component GO Annotation Evidence References Source
is active in neuronal dense core vesicle IDA
IDA: Inferred from direct assay
25248098 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dmX-like protein 2

  • rabconnectin-3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03837 DMXL2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dmxl2 NCBI NCBI:23312