Slc17a5 - solute carrier family 17 (anion/sugar transporter), member 5 Gene

Also Known as SD; AST; NSD; SLD; ISSD; SIASD; SIALIN; 4732491M05; 4631416G20Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 235504

Summary

Predicted to enable sialic acid transmembrane transporter activity. Acts upstream of or within response to bacterium. Located in cytoplasmic vesicle and plasma membrane. Is expressed in several structures, including gut; liver; metanephros; nervous system; and sensory organ epithelium. Used to study lysosomal storage disease and sialuria. Human ortholog(s) of this gene implicated in sialuria. Orthologous to human SLC17A5 (solute carrier family 17 member 5). [provided by Alliance of Genome Resources, Apr 2022]

Slc17a5 Products (2)

mRNA Protein Name
NM_001276452.1 NP_001263381.1 sialin isoform b
NM_172773.3 NP_766361.1 sialin isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables D-glucuronate transmembrane transporter activity IMP
IMP: Inferred from mutant phenotype
10581036 MGI
Biological Process GO Annotation Evidence References Source
involved in neurotransmitter loading into synaptic vesicle EXP
EXP: Inferred from Experiment
18695252 MGI
involved in neurotransmitter loading into synaptic vesicle IDA
IDA: Inferred from direct assay
18695252 MGI
involved in neurotransmitter loading into synaptic vesicle IEP
IEP: Inferred from expression pattern
18695252 MGI
involved in neurotransmitter loading into synaptic vesicle IMP
IMP: Inferred from mutant phenotype
18695252 MGI
acts upstream of or within response to bacterium IEP
IEP: Inferred from expression pattern
23012479 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasmic vesicle IDA
IDA: Inferred from direct assay
15006695 MGI
is active in glutamatergic synapse EXP
EXP: Inferred from Experiment
18695252 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
18695252 MGI
is active in glutamatergic synapse IEP
IEP: Inferred from expression pattern
18695252 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
18695252 MGI
is active in lysosomal membrane IMP
IMP: Inferred from mutant phenotype
10581036 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
15006695 MGI
is active in synaptic vesicle membrane IDA
IDA: Inferred from direct assay
18695252 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sialin

  • H(+)/nitrate cotransporter

  • sodium/sialic acid cotransporter

  • vesicular H(+)/Aspartate-glutamate cotransporter

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13038 SLC17A5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc17a5 NCBI NCBI:26503