Arhgef9 - CDC42 guanine nucleotide exchange factor (GEF) 9 Gene
Also Known as 9630036L12Rik
Species: Mus musculus
Gene Type: protein coding
Gene ID: 236915
Summary
Predicted to enable guanyl-nucleotide exchange factor activity. Involved in regulation of postsynaptic specialization assembly. Located in GABA-ergic synapse and postsynaptic density. Is expressed in several structures, including central nervous system; dorsal root ganglion; and ear. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 8. Orthologous to human ARHGEF9 (Cdc42 guanine nucleotide exchange factor 9). [provided by Alliance of Genome Resources, Apr 2022]
Arhgef9 Products (21)
| mRNA | Protein | Name |
|---|---|---|
| NM_001033329.4 | NP_001028501.1 | rho guanine nucleotide exchange factor 9 isoform a |
| NM_001290384.2 | NP_001277313.1 | rho guanine nucleotide exchange factor 9 isoform b |
| NM_001290385.2 | NP_001277314.1 | rho guanine nucleotide exchange factor 9 isoform b |
| NM_001405901.1 | NP_001392830.1 | rho guanine nucleotide exchange factor 9 isoform c |
| NM_001405902.1 | NP_001392831.1 | rho guanine nucleotide exchange factor 9 isoform d |
| NM_001405903.1 | NP_001392832.1 | rho guanine nucleotide exchange factor 9 isoform e |
| NM_001405904.1 | NP_001392833.1 | rho guanine nucleotide exchange factor 9 isoform f |
| NM_001405905.1 | NP_001392834.1 | rho guanine nucleotide exchange factor 9 isoform a |
| NM_001405906.1 | NP_001392835.1 | rho guanine nucleotide exchange factor 9 isoform g |
| NM_001405907.1 | NP_001392836.1 | rho guanine nucleotide exchange factor 9 isoform h |
| NM_001405908.1 | NP_001392837.1 | rho guanine nucleotide exchange factor 9 isoform b |
| NM_001405909.1 | NP_001392838.1 | rho guanine nucleotide exchange factor 9 isoform b |
| NM_001405910.1 | NP_001392839.1 | rho guanine nucleotide exchange factor 9 isoform i |
| NM_001405911.1 | NP_001392840.1 | rho guanine nucleotide exchange factor 9 isoform j |
| NM_001405912.1 | NP_001392841.1 | rho guanine nucleotide exchange factor 9 isoform k |
| NM_001405913.1 | NP_001392842.1 | rho guanine nucleotide exchange factor 9 isoform l |
| NM_001405914.1 | NP_001392843.1 | rho guanine nucleotide exchange factor 9 isoform l |
| NM_001405915.1 | NP_001392844.1 | rho guanine nucleotide exchange factor 9 isoform m |
| NM_001405916.1 | NP_001392845.1 | rho guanine nucleotide exchange factor 9 isoform n |
| NM_001405917.1 | NP_001392846.1 | rho guanine nucleotide exchange factor 9 isoform n |
| NM_001405918.1 | NP_001392847.1 | rho guanine nucleotide exchange factor 9 isoform n |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in regulation of postsynaptic specialization assembly |
IDA
IDA: Inferred from direct assay
|
17690689 | MGI |
| involved in regulation of postsynaptic specialization assembly |
IMP
IMP: Inferred from mutant phenotype
|
17690689 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| is active in GABA-ergic synapse |
IDA
IDA: Inferred from direct assay
|
17690689 | MGI |
| is active in GABA-ergic synapse |
IMP
IMP: Inferred from mutant phenotype
|
17690689 | MGI |
| located in postsynaptic density |
IDA
IDA: Inferred from direct assay
|
27609886 | MGI |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
rho guanine nucleotide exchange factor 9 |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(1)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS00965 | ARHGEF9 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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