Tmtc3 - transmembrane and tetratricopeptide repeat containing 3 Gene

Also Known as mSmile; 9130014E20Rik; B130008E12Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 237500

Summary

Predicted to enable mannosyltransferase activity. Acts upstream of or within several processes, including lung development; muscle cell development; and post-embryonic development. Predicted to be located in endoplasmic reticulum. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and trunk mesenchyme. Human ortholog(s) of this gene implicated in lissencephaly 8. Orthologous to human TMTC3 (transmembrane O-mannosyltransferase targeting Cadherins 3). [provided by Alliance of Genome Resources, Apr 2022]

Tmtc3 Products (2)

mRNA Protein Name
NM_001033332.2 NP_001028504.1 protein O-mannosyl-transferase TMTC3 isoform 2
NM_001110013.1 NP_001103483.1 protein O-mannosyl-transferase TMTC3 isoform 1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within bud outgrowth involved in lung branching IMP
IMP: Inferred from mutant phenotype
21956870 MGI
acts upstream of or within cell differentiation IMP
IMP: Inferred from mutant phenotype
21956870 MGI
acts upstream of or within lung alveolus development IMP
IMP: Inferred from mutant phenotype
21956870 MGI
acts upstream of or within lung development IMP
IMP: Inferred from mutant phenotype
21956870 MGI
acts upstream of or within muscle cell development IMP
IMP: Inferred from mutant phenotype
21956870 MGI
acts upstream of or within post-embryonic development IMP
IMP: Inferred from mutant phenotype
21956870 MGI
acts upstream of or within regulation of gene expression IMP
IMP: Inferred from mutant phenotype
21956870 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein O-mannosyl-transferase TMTC3

  • transmembrane and TPR repeat-containing protein 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14778 TMTC3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tmtc3 NCBI NCBI:160418