Osbpl8 - oxysterol binding protein-like 8 Gene

Also Known as ORP-8; C730029P18Rik; D330025H14Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 237542

Summary

This gene encodes a member of the oxysterol-binding protein (Osbp) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal Osbp-like sterol-binding domain. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Osbpl8 Products (2)

mRNA Protein Name
NM_001003717.1 NP_001003717.1 oxysterol-binding protein-related protein 8 isoform b
NM_175489.3 NP_780698.2 oxysterol-binding protein-related protein 8 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21441927 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of cell migration IMP
IMP: Inferred from mutant phenotype
21441927 MGI
involved in positive regulation of D-glucose import IMP
IMP: Inferred from mutant phenotype
23812417 MGI
involved in positive regulation of insulin receptor signaling pathway IDA
IDA: Inferred from direct assay
23812417 MGI
acts upstream of or within positive regulation of insulin receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
21441927 MGI
acts upstream of or within positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IMP
IMP: Inferred from mutant phenotype
21441927 MGI
involved in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IMP
IMP: Inferred from mutant phenotype
23812417 MGI
acts upstream of or within protein localization to nuclear pore IMP
IMP: Inferred from mutant phenotype
21441927 MGI
Cellular Component GO Annotation Evidence References Source
located in nuclear membrane IMP
IMP: Inferred from mutant phenotype
22683860 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

oxysterol-binding protein-related protein 8

  • OSBP-related protein 8

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09845 OSBPL8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Osbpl8 NCBI NCBI:114882