Stac3 - SH3 and cysteine rich domain 3 Gene

Also Known as 9830125E18

Species: Mus musculus

Gene Type: protein coding
Gene ID: 237611

Summary

Predicted to enable identical protein binding activity. Involved in positive regulation of protein localization to plasma membrane and positive regulation of voltage-gated Calcium Channel activity. Acts upstream of or within skeletal muscle fiber development. Located in cytosol. Is extrinsic component of cytoplasmic side of plasma membrane. Part of voltage-gated Calcium Channel complex. Is expressed in limb musculature; somite; and tongue. Human ortholog(s) of this gene implicated in Native American myopathy. Orthologous to human STAC3 (SH3 and cysteine rich domain 3). [provided by Alliance of Genome Resources, Apr 2022]

Stac3 Products (2)

mRNA Protein Name
NM_001359751.1 NP_001346680.1 SH3 and cysteine-rich domain-containing protein 3
NM_177707.4 NP_808375.1 SH3 and cysteine-rich domain-containing protein 3

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in positive regulation of protein localization to plasma membrane IMP
IMP: Inferred from mutant phenotype
27621462 MGI
involved in positive regulation of voltage-gated calcium channel activity IMP
IMP: Inferred from mutant phenotype
27621462 MGI
acts upstream of or within skeletal muscle fiber development IMP
IMP: Inferred from mutant phenotype
23626854 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasmic side of plasma membrane IDA
IDA: Inferred from direct assay
28112192 MGI
located in cytosol IDA
IDA: Inferred from direct assay
28112192 MGI
part of voltage-gated calcium channel complex IDA
IDA: Inferred from direct assay
28112192 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

SH3 and cysteine-rich domain-containing protein 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13865 STAC3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Stac3 NCBI NCBI:246329