Smcr8 - Smith-Magenis syndrome chromosome region, candidate 8 homolog (human) Gene

Also Known as 2310076G09Rik; D030073L15Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 237782

Summary

Predicted to enable protein kinase binding activity and protein kinase inhibitor activity. Predicted to contribute to guanyl-nucleotide exchange factor activity. Involved in regulation of Autophagy. Located in cytoplasm. Orthologous to human SMCR8 (SMCR8-C9orf72 complex subunit). [provided by Alliance of Genome Resources, Apr 2022]

Smcr8 Products (2)

mRNA Protein Name
NM_001085440.1 NP_001078909.1 guanine nucleotide exchange protein SMCR8 isoform 1
NM_175491.4 NP_780700.1 guanine nucleotide exchange protein SMCR8 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
27875531 MGI
Biological Process GO Annotation Evidence References Source
involved in regulation of autophagy IMP
IMP: Inferred from mutant phenotype
27617292 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
27617292 MGI
located in postsynapse IDA
IDA: Inferred from direct assay
31651360 MGI
located in presynapse IDA
IDA: Inferred from direct assay
31651360 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

guanine nucleotide exchange protein SMCR8

  • smith-Magenis syndrome chromosomal region candidate gene 8 protein homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13428 SMCR8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Smcr8 NCBI NCBI:140775