Dnah9 - dynein, axonemal, heavy chain 9 Gene

Also Known as Dnahc9; mKIAA0357; 9030022M04; A230091C01; C230051G16; D11Ertd686e

Species: Mus musculus

Gene Type: protein coding
Gene ID: 237806

Summary

Predicted to enable dynein intermediate chain binding activity; dynein light intermediate chain binding activity; and minus-end-directed microtubule motor activity. Acts upstream of or within cerebrospinal fluid circulation and mucociliary clearance. Located in 9+2 motile cilium and distal portion of axoneme. Part of outer dynein arm. Is expressed in central nervous system and testis. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 40. Orthologous to human DNAH9 (dynein axonemal heavy chain 9). [provided by Alliance of Genome Resources, Apr 2022]

Dnah9 Products (1)

mRNA Protein Name
NM_001099633.1 NP_001093103.1 dynein heavy chain 9, axonemal

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within cerebrospinal fluid circulation IMP
IMP: Inferred from mutant phenotype
33347437 MGI
acts upstream of or within establishment of localization in cell IMP
IMP: Inferred from mutant phenotype
33347437 MGI
acts upstream of or within mucociliary clearance IMP
IMP: Inferred from mutant phenotype
33347437 MGI
Cellular Component GO Annotation Evidence References Source
located in 9+2 motile cilium IDA
IDA: Inferred from direct assay
23525783 MGI
located in distal portion of axoneme IDA
IDA: Inferred from direct assay
33347437 MGI
part of outer dynein arm IDA
IDA: Inferred from direct assay
27353389 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dynein heavy chain 9, axonemal

  • dynein, axonemal, heavy polypeptide 9

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03854 DNAH9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22472 Dnah9 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28995 Dnah9 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dnah9 NCBI NCBI:1770