Slfn14 - schlafen 14 Gene

Also Known as Gm20; Slfn14-ps

Species: Mus musculus

Gene Type: protein coding
Gene ID: 237890

Summary

Enables endoribonuclease activity and ribosome binding activity. Involved in RNA phosphodiester bond hydrolysis, endonucleolytic; mRNA catabolic process; and rRNA catabolic process. Located in nucleus. Human ortholog(s) of this gene implicated in platelet-type bleeding disorder 20. Orthologous to human SLFN14 (schlafen family member 14). [provided by Alliance of Genome Resources, Apr 2022]

Slfn14 Products (1)

mRNA Protein Name
NM_001166028.1 NP_001159500.1 protein SLFN14

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables RNA endonuclease activity IDA
IDA: Inferred from direct assay
25996083 MGI
enables ribosome binding IDA
IDA: Inferred from direct assay
25996083 MGI
Biological Process GO Annotation Evidence References Source
involved in mRNA catabolic process IDA
IDA: Inferred from direct assay
25996083 MGI
involved in rRNA catabolic process IDA
IDA: Inferred from direct assay
25996083 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
25996083 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein SLFN14

  • Schlafen family member 14, CAST_EiJ strain specific

  • Schlafen family member 14, WSB_EiJ strain specific

  • schlafen family member 14, pseudogene

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13367 SLFN14 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slfn14 NCBI NCBI:342618