2. Gene
  3. Def8 - differentially expressed in FDCP 8 Gene

Def8 - differentially expressed in FDCP 8 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as DEF-8; D8Ertd713e

Gene ID: 23854 | Gene type: protein coding

About Def8

Summary

Predicted to enable metal ion binding activity. Involved in lysosome localization; positive regulation of bone resorption; and positive regulation of ruffle assembly. Is expressed in several structures, including brain; genitourinary system; liver; retina nuclear layer; and spleen. Orthologous to human DEF8 (differentially expressed in FDCP 8 homolog). [provided by Alliance of Genome Resources, Apr 2022]

Def8 Products(19)

mRNA Protein Name
NM_001253783.2 NP_001240712.1 differentially expressed in FDCP 8 isoform 1
NM_001253784.2 NP_001240713.1 differentially expressed in FDCP 8 isoform 2
NM_001281803.2 NP_001268732.1 differentially expressed in FDCP 8 isoform 3
NM_001414280.1 NP_001401209.1 differentially expressed in FDCP 8 isoform 4
NM_001414281.1 NP_001401210.1 differentially expressed in FDCP 8 isoform 5
NM_001414282.1 NP_001401211.1 differentially expressed in FDCP 8 isoform 1
NM_001414283.1 NP_001401212.1 differentially expressed in FDCP 8 isoform 2
NM_001414284.1 NP_001401213.1 differentially expressed in FDCP 8 isoform 2
NM_001414285.1 NP_001401214.1 differentially expressed in FDCP 8 isoform 3
NM_001414286.1 NP_001401215.1 differentially expressed in FDCP 8 isoform 3
NM_001414287.1 NP_001401216.1 differentially expressed in FDCP 8 isoform 3
NM_001414288.1 NP_001401217.1 differentially expressed in FDCP 8 isoform 8
NM_001414289.1 NP_001401218.1 differentially expressed in FDCP 8 isoform 9
NM_001414290.1 NP_001401219.1 differentially expressed in FDCP 8 isoform 10
NM_001414291.1 NP_001401220.1 differentially expressed in FDCP 8 isoform 11
NM_001414292.1 NP_001401221.1 differentially expressed in FDCP 8 isoform 11
NM_001414293.1 NP_001401222.1 differentially expressed in FDCP 8 isoform 12
NM_001414294.1 NP_001401223.1 differentially expressed in FDCP 8 isoform 13
NM_054046.6 NP_473387.1 differentially expressed in FDCP 8 isoform 3
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
27777970 MGI
Biological Process GO Annotation Evidence Reference Source
involved in lysosome localization IMP
IMP: Inferred from mutant phenotype
27777970 MGI
involved in positive regulation of bone resorption IMP
IMP: Inferred from mutant phenotype
27777970 MGI
involved in positive regulation of ruffle assembly IMP
IMP: Inferred from mutant phenotype
27777970 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

differentially expressed in FDCP 8

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03672 DEF8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Def8 NCBI NCBI:54849