Hs2st1 - heparan sulfate 2-O-sulfotransferase 1 Gene

Also Known as 2OST; Hs2st; mKIAA0448

Species: Mus musculus

Gene Type: protein coding
Gene ID: 23908

Summary

Enables heparan sulfate 2-O-sulfotransferase activity. Acts upstream of or within several processes, including heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; heparin metabolic process; and ureteric bud formation. Predicted to be located in Golgi apparatus and membrane. Predicted to be integral component of membrane. Is expressed in brain and future brain. Orthologous to human HS2ST1 (heparan sulfate 2-O-sulfotransferase 1). [provided by Alliance of Genome Resources, Apr 2022]

Hs2st1 Products (2)

mRNA Protein Name
NM_001355234.1 NP_001342163.1 heparan sulfate 2-O-sulfotransferase 1 isoform 1
NM_011828.4 NP_035958.3 heparan sulfate 2-O-sulfotransferase 1 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables heparan sulfate 2-O-sulfotransferase activity IDA
IDA: Inferred from direct assay
15226404 MGI
enables heparan sulfate 2-O-sulfotransferase activity IMP
IMP: Inferred from mutant phenotype
11457822 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within gene expression IMP
IMP: Inferred from mutant phenotype
32201365 MGI
involved in heparan sulfate proteoglycan biosynthetic process IMP
IMP: Inferred from mutant phenotype
19889634 MGI
acts upstream of or within heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process IMP
IMP: Inferred from mutant phenotype
11457822 MGI
acts upstream of or within heparin metabolic process IMP
IMP: Inferred from mutant phenotype
11457822 MGI
acts upstream of or within ureteric bud formation IMP
IMP: Inferred from mutant phenotype
9637690 MGI
Cellular Component GO Annotation Evidence References Source
is active in Golgi apparatus IDA
IDA: Inferred from direct assay
11687650 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

heparan sulfate 2-O-sulfotransferase 1

  • 2-O-sulfotransferase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06376 HS2ST1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hs2st1 NCBI NCBI:9653