Lnpep - leucyl/cystinyl aminopeptidase Gene

Also Known as CAP; IRAP; PLAP; gp160; vp165; 2010309L07Rik; 4732490P18Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 240028

Summary

Enables Aminopeptidase activity. Involved in negative regulation of cold-induced thermogenesis. Acts upstream of or within SMAD protein signal transduction and protein catabolic process. Located in cytoplasmic vesicle membrane; perinuclear region of cytoplasm; and plasma membrane. Is expressed in extraembryonic component; labyrinthine zone; and placenta. Orthologous to human LNPEP (leucyl and cystinyl Aminopeptidase). [provided by Alliance of Genome Resources, Apr 2022]

Lnpep Products (1)

mRNA Protein Name
NM_172827.3 NP_766415.1 leucyl-cystinyl aminopeptidase

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables aminopeptidase activity IMP
IMP: Inferred from mutant phenotype
11884418 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
15800058 MGI
Biological Process GO Annotation Evidence References Source
involved in negative regulation of cold-induced thermogenesis IMP
IMP: Inferred from mutant phenotype
25534853 MGI
acts upstream of or within protein catabolic process IMP
IMP: Inferred from mutant phenotype
11884418 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasmic vesicle membrane IDA
IDA: Inferred from direct assay
12490950 MGI
located in membrane IMP
IMP: Inferred from mutant phenotype
11884418 MGI
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
15800058 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
15800058 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

leucyl-cystinyl aminopeptidase

  • OTase

  • cystinyl aminopeptidase

  • oxytocinase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07730 LNPEP Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lnpep NCBI NCBI:4012