Dlgap2 - DLG associated protein 2 Gene

Also Known as Dap2; Dap-2; Sapap2; 6430596N04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 244310

Summary

Predicted to enable molecular adaptor activity and protein domain specific binding activity. Involved in regulation of postsynaptic neurotransmitter receptor activity. Predicted to be located in dendritic spine. Predicted to be active in glutamatergic synapse and postsynaptic specialization. Is expressed in cranium and nervous system. Orthologous to human DLGAP2 (DLG associated protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Dlgap2 Products (2)

mRNA Protein Name
NM_001145965.1 NP_001139437.1 disks large-associated protein 2 isoform 2
NM_172910.3 NP_766498.2 disks large-associated protein 2 isoform 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in modulation of chemical synaptic transmission IDA
IDA: Inferred from direct assay
25071926 MGI
involved in modulation of chemical synaptic transmission IMP
IMP: Inferred from mutant phenotype
25071926 MGI
involved in regulation of postsynaptic neurotransmitter receptor activity IDA
IDA: Inferred from direct assay
25071926 MGI
involved in regulation of postsynaptic neurotransmitter receptor activity IMP
IMP: Inferred from mutant phenotype
25071926 MGI
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
19640847 MGI
is active in glutamatergic synapse IEP
IEP: Inferred from expression pattern
19640847 MGI
is active in postsynaptic density, intracellular component IDA
IDA: Inferred from direct assay
19640847 MGI
is active in postsynaptic density, intracellular component IEP
IEP: Inferred from expression pattern
19640847 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

disks large-associated protein 2

  • PSD-95/SAP90-binding protein 2

  • SAP90/PSD-95 associated protein 2

  • discs, large homolog-associated protein 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03802 DLGAP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dlgap2 NCBI NCBI:9228