2. Gene
  3. Zc4h2 - zinc finger, C4H2 domain containing Gene

Zc4h2 - zinc finger, C4H2 domain containing Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Gm372; mKIAA1166

Gene ID: 245522 | Gene type: protein coding

About Zc4h2

Summary

Predicted to enable metal ion binding activity. Acts upstream of or within several processes, including noradrenergic neuron development; positive regulation of DNA-binding transcription factor activity; and protein monoubiquitination. Located in neuronal cell body. Is expressed in nervous system and neural retina. Human ortholog(s) of this gene implicated in Miles-Carpenter syndrome. Orthologous to human ZC4H2 (zinc finger C4H2-type containing). [provided by Alliance of Genome Resources, Apr 2022]

Zc4h2 Products(3)

mRNA Protein Name
NM_001003916.2 NP_001003916.1 zinc finger C4H2 domain-containing protein isoform 1
NM_001289696.1 NP_001276625.1 zinc finger C4H2 domain-containing protein isoform 2
NM_001289697.1 NP_001276626.1 zinc finger C4H2 domain-containing protein isoform 3
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
32094113 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within noradrenergic neuron development IMP
IMP: Inferred from mutant phenotype
32094113 MGI
acts upstream of or within positive regulation of DNA-binding transcription factor activity IGI
IGI: Inferred from genetic interaction
32094113 MGI
acts upstream of or within protein monoubiquitination IGI
IGI: Inferred from genetic interaction
32094113 MGI
acts upstream of or within regulation of transcription regulatory region DNA binding IGI
IGI: Inferred from genetic interaction
32094113 MGI
Cellular Component GO Annotation Evidence Reference Source
located in neuronal cell body IDA
IDA: Inferred from direct assay
32094113 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

zinc finger C4H2 domain-containing protein

hepatocellular carcinoma-associated antigen 127 homolog

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15999 ZC4H2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Zc4h2 NCBI NCBI:55906