Lmbrd1 - LMBR1 domain containing 1 Gene

Also Known as LMBD1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 246046

Summary

Predicted to enable AP-2 adaptor complex binding activity; clathrin heavy chain binding activity; and Insulin Receptor binding activity. Predicted to be involved in gastrulation; protein localization to lysosome; and receptor-mediated endocytosis. Predicted to act upstream of or within negative regulation of glucose import; negative regulation of Insulin Receptor signaling pathway; and negative regulation of protein kinase B signaling. Predicted to be located in several cellular components, including clathrin-coated endocytic vesicle; endoplasmic reticulum membrane; and lysosome. Predicted to be active in lysosomal membrane. Human ortholog(s) of this gene implicated in methylmalonic aciduria and homocystinuria type cblF. Orthologous to human LMBRD1 (LMBR1 domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Lmbrd1 Products (1)

mRNA Protein Name
NM_139189.2 NP_631928.2 lysosomal cobalamin transport escort protein LMBD1
Protein Preferred Names Protein Names

lysosomal cobalamin transport escort protein LMBD1

  • LMBR1 domain-containing protein 1

  • liver regeneration p-53 related protein

  • probable lysosomal cobalamin transporter

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07708 LMBRD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lmbrd1 NCBI NCBI:55788