CTAG1A - cancer/testis antigen 1A Gene

Also Known as ESO1; CT6.1; LAGE-2; LAGE2A; NY-ESO-1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 246100

About CTAG1A

Cytogenetic location: Xq28 Genomic coordinates (GRCh38): X:154,585,133-154,586,816 (from NCBI)

This gene has 2 transcripts (splice variants), 171 orthologues and 3 paralogues. Restricted expression toward testis (RPKM 4.4).

Summary

The protein encoded by this gene is a tumor cell antigen found in various types of cancers, which makes it a good candidate for a Cancer vaccine. This gene is also highly expressed in normal ovary and testis tissues. An identical copy of this gene is found on the same chromosome. [provided by RefSeq, Dec 2015]

CTAG1A Products (1)

mRNA Protein Name
NM_139250.2 NP_640343.1 cancer/testis antigen 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
17137291 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cancer/testis antigen 1

  • New York Esophageal Squamous Cell Carcinoma 1

Related Diseases

Diseases Alias
Synovium Cancer

  • Malignant Tumor Of Synovium

  • Synovial Neoplasm
Cellular Myxoid Liposarcoma

  • Round Cell Liposarcoma
Subclavian Steal Syndrome

  • Subclavian Artery Stenosis

  • Subclavian Steal Phenomenon

  • Subclavian Steal Steno-Occlusive Disease

  • Subclavian Steal
Myxoid Liposarcoma

  • Myxoid/Round Cell Liposarcoma

  • Liposarcoma, Myxoid

  • Mrcls

  • Myxoliposarcoma

  • MXLIPO

  • Liposarcoma Myxoid

  • Liposarcoma
Sarcoma, Synovial

  • Synovial Sarcoma

  • Synovialosarcoma

  • Synovial Cell Sarcoma

  • Sarcoma Synovial
Epithelioid Cell Synovial Sarcoma

  • Synovial Sarcoma, Epithelioid Cell

  • Epithelioid Synovial Sarcoma
Dedifferentiated Liposarcoma

  • Ddls

  • Liposarcoma Dedifferentiated

  • Liposarcoma, Dedifferentiated
Small Intestine Leiomyosarcoma

  • Leiomyosarcoma Of The Small Bowel

  • Smooth Muscle Connective Tissue Tumor

  • Leiomyosarcoma Of Small Intestine
Esophageal Cancer

  • Esophageal Carcinoma

  • Carcinoma Of Esophagus

  • Esophageal Squamous Cell Carcinoma, Somatic

  • Esophageal Carcinoma, Somatic

  • Esophagus Cancer

  • Gastric Cardia Adenocarcinoma

  • Esophageal Neoplasms

  • Esophageal Cancer, Somatic

  • Cancer Of Esophagus

  • Cancer Of Oesophagus

  • Carcinoma Of Oesophagus

  • Ca Lower Third Oesophagus

  • Ca Middle Third Oesophagus

  • Malignant Neoplasm Of Distal Third Of Esophagus

  • Malignant Neoplasm Of Lower Third Of Oesophagus

  • Malignant Neoplasm Of Middle Third Of Oesophagus

  • Malignant Neoplasm Of Proximal Third Of Esophagus

  • Malignant Neoplasm Of Upper Third Esophagus

  • Malignant Tumor Of Abdominal Esophagus

  • Malignant Tumor Of Distal Third Of Esophagus

  • Malignant Tumor Of Proximal Third Of Esophagus

  • Malignant Tumor Of The Middle Third Of The Esophagus

  • ESCR

  • Aerodigestive Tract Cancer

  • Escc

  • Esophageal Squamous Cell Carcinoma

  • Cancer, Esophageal

  • Malignant Neoplasm Of Esophagus

  • Squamous Cell Carcinoma Of Esophagus

  • Malignant Neoplasm Of Middle Third Of Esophagus
Wilms Tumor 1

  • Nephroblastoma

  • Wilms Tumor

  • WT1

  • Wilms' Tumor

  • Bilateral Wilms Tumor

  • Wilms Tumor, Type 1

  • Wilms Tumor, Somatic

  • Adult Nephroblastoma

  • Wt1 Disorder

  • Renal Embryonic Tumor

  • Adult Kidney Wilms Tumor

  • Childhood Kidney Wilms Tumor

  • Nonanaplastic Kidney Wilms Tumor
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03280 CTAG1A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus CTAG1A MGD MGI:3644285