Myo1g - myosin IG Gene

Also Known as E430002D17Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 246177

Summary

Enables phosphatidylinositol-3,4,5-trisphosphate binding activity; phosphatidylinositol-3,4-bisphosphate binding activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in Fc-gamma Receptor signaling pathway involved in phagocytosis and T cell mediated immunity. Acts upstream of or within several processes, including T cell meandering migration; cell gliding; and phagocytosis. Located in several cellular components, including lamellipodium; microvillus; and phagocytic cup. Orthologous to human MYO1G (Myosin IG). [provided by Alliance of Genome Resources, Apr 2022]

Myo1g Products (1)

mRNA Protein Name
NM_178440.4 NP_848534.2 unconventional myosin-Ig

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables phosphatidylinositol-3,4,5-trisphosphate binding IDA
IDA: Inferred from direct assay
23038771 MGI
enables phosphatidylinositol-3,4-bisphosphate binding IDA
IDA: Inferred from direct assay
23038771 MGI
enables phosphatidylinositol-4,5-bisphosphate binding IDA
IDA: Inferred from direct assay
23038771 MGI
Biological Process GO Annotation Evidence References Source
involved in Fc-gamma receptor signaling pathway involved in phagocytosis IMP
IMP: Inferred from mutant phenotype
23038771 MGI
acts upstream of or within T cell meandering migration IMP
IMP: Inferred from mutant phenotype
25083865 MGI
involved in T cell mediated immunity IMP
IMP: Inferred from mutant phenotype
25083865 MGI
acts upstream of or within cell gliding IMP
IMP: Inferred from mutant phenotype
24310084 MGI
acts upstream of or within cell-substrate adhesion IMP
IMP: Inferred from mutant phenotype
24310084 MGI
acts upstream of or within establishment of localization in cell IMP
IMP: Inferred from mutant phenotype
24310084 MGI
acts upstream of or within exocytosis IMP
IMP: Inferred from mutant phenotype
24310084 MGI
acts upstream of or within phagocytosis IMP
IMP: Inferred from mutant phenotype
24310084 MGI
Cellular Component GO Annotation Evidence References Source
located in filopodium IDA
IDA: Inferred from direct assay
24310084 MGI
located in lamellipodium IDA
IDA: Inferred from direct assay
24310084 MGI
located in leading edge membrane IDA
IDA: Inferred from direct assay
25083865 MGI
located in microvillus IDA
IDA: Inferred from direct assay
24310084 MGI
located in phagocytic cup IDA
IDA: Inferred from direct assay
23038771 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
19968988 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

unconventional myosin-Ig

  • myosin 1G

  • myosin-Ig

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08943 MYO1G Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Myo1g NCBI NCBI:64005