2. Gene
  3. Myo1g - myosin IG Gene

Myo1g - myosin IG Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as E430002D17Rik

Gene ID: 246177 | Gene type: protein coding

About Myo1g

Summary

Enables phosphatidylinositol-3,4,5-trisphosphate binding activity; phosphatidylinositol-3,4-bisphosphate binding activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in Fc-gamma Receptor signaling pathway involved in phagocytosis and T cell mediated immunity. Acts upstream of or within several processes, including T cell meandering migration; cell gliding; and phagocytosis. Located in several cellular components, including lamellipodium; microvillus; and phagocytic cup. Orthologous to human MYO1G (Myosin IG). [provided by Alliance of Genome Resources, Apr 2022]

Myo1g Products(1)

mRNA Protein Name
NM_178440.4 NP_848534.2 unconventional myosin-Ig
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables phosphatidylinositol-3,4,5-trisphosphate binding IDA
IDA: Inferred from direct assay
23038771 MGI
enables phosphatidylinositol-3,4-bisphosphate binding IDA
IDA: Inferred from direct assay
23038771 MGI
enables phosphatidylinositol-4,5-bisphosphate binding IDA
IDA: Inferred from direct assay
23038771 MGI
Biological Process GO Annotation Evidence Reference Source
involved in Fc-gamma receptor signaling pathway involved in phagocytosis IMP
IMP: Inferred from mutant phenotype
23038771 MGI
acts upstream of or within T cell meandering migration IMP
IMP: Inferred from mutant phenotype
25083865 MGI
involved in T cell mediated immunity IMP
IMP: Inferred from mutant phenotype
25083865 MGI
acts upstream of or within cell gliding IMP
IMP: Inferred from mutant phenotype
24310084 MGI
acts upstream of or within cell-substrate adhesion IMP
IMP: Inferred from mutant phenotype
24310084 MGI
acts upstream of or within establishment of localization in cell IMP
IMP: Inferred from mutant phenotype
24310084 MGI
acts upstream of or within exocytosis IMP
IMP: Inferred from mutant phenotype
24310084 MGI
acts upstream of or within phagocytosis IMP
IMP: Inferred from mutant phenotype
24310084 MGI
Cellular Component GO Annotation Evidence Reference Source
located in filopodium IDA
IDA: Inferred from direct assay
24310084 MGI
located in lamellipodium IDA
IDA: Inferred from direct assay
24310084 MGI
located in leading edge membrane IDA
IDA: Inferred from direct assay
25083865 MGI
located in microvillus IDA
IDA: Inferred from direct assay
24310084 MGI
located in phagocytic cup IDA
IDA: Inferred from direct assay
23038771 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
19968988 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

unconventional myosin-Ig

myosin 1G

myosin-Ig

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08943 MYO1G Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Myo1g NCBI NCBI:64005