Pygm - glycogen phosphorylase, muscle associated Gene

Also Known as Muscpho

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24701

Summary

Enables anion binding activity; carbohydrate binding activity; and glycogen Phosphorylase activity. Involved in several processes, including glycogen catabolic process; response to cAMP; and response to hypoxia. Located in sarcoplasmic reticulum. Used to study cholestasis. Human ortholog(s) of this gene implicated in glycogen storage disease V. Orthologous to human PYGM (glycogen Phosphorylase, muscle associated). [provided by Alliance of Genome Resources, Apr 2022]

Pygm Products (1)

mRNA Protein Name
NM_012638.1 NP_036770.1 glycogen phosphorylase, muscle form

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables AMP binding IDA
IDA: Inferred from direct assay
14674711 RGD
enables carbohydrate binding IDA
IDA: Inferred from direct assay
6449198 RGD
enables glycogen phosphorylase activity IDA
IDA: Inferred from direct assay
6244274 RGD
enables organic cyclic compound binding IDA
IDA: Inferred from direct assay
17095214 RGD
enables pyridoxal phosphate binding IDA
IDA: Inferred from direct assay
11692172 RGD
Biological Process GO Annotation Evidence References Source
involved in glycogen catabolic process IDA
IDA: Inferred from direct assay
6449198 RGD
involved in glycogen metabolic process IDA
IDA: Inferred from direct assay
6244274 RGD
involved in intracellular calcium ion homeostasis IDA
IDA: Inferred from direct assay
8810099 RGD
involved in response to cAMP IDA
IDA: Inferred from direct assay
14579114 RGD
involved in response to hypoxia IDA
IDA: Inferred from direct assay
14674711 RGD
Cellular Component GO Annotation Evidence References Source
located in sarcoplasmic reticulum IDA
IDA: Inferred from direct assay
11692172 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glycogen phosphorylase, muscle form

  • Phosphorylase glycogen

  • Phosphorylase, glycogen

  • muscle (McArdle syndrome)

  • muscle (McArdle syndrome)

  • muscle glycogen phosphorylase

  • myophosphorylase

  • phosphorylase, glycogen, muscle

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11490 PYGM Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pygm NCBI NCBI:5837