Scnn1b - sodium channel epithelial 1 subunit beta Gene

Rattus norvegicus

Also known as RNENACB

Gene ID: 24767 | Gene type: protein coding

About Scnn1b

Summary

Enables WW domain binding activity and ligand-gated Sodium Channel activity. Contributes to sodium ion transmembrane transporter activity. Involved in several processes, including response to hypoxia; sodium ion transport; and wound healing, spreading of epidermal cells. Located in apical plasma membrane and cell surface. Used to study nephrotic syndrome. Human ortholog(s) of this gene implicated in Liddle syndrome; autosomal recessive pseudohypoaldosteronism type 1; bronchiectasis 1; and pseudohypoaldosteronism. Orthologous to human SCNN1B (Sodium Channel epithelial 1 subunit beta). [provided by Alliance of Genome Resources, Apr 2022]

Scnn1b Products(1)

mRNA	Protein	Name
NM_012648.1	NP_036780.1	amiloride-sensitive sodium channel subunit beta

Protein Preferred Names

Protein Names

amiloride-sensitive sodium channel subunit beta

SCNEB	beta-ENaC
beta-NaCH	epithelial Na(+) channel subunit beta
nonvoltage-gated sodium channel 1 subunit beta	sodium channel epithelial 1 beta subunit
sodium channel, non-voltage-gated 1, beta subunit	sodium channel, nonvoltage-gated, type I, beta

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12553	SCNN1B Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Scnn1b	NCBI	NCBI:6338

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