1. Gene
  2. Slc9a4 - solute carrier family 9 member A4 Gene

Slc9a4 - solute carrier family 9 member A4 Gene

Rattus norvegicus

Also known as Nhe4

Gene ID: 24785 | Gene type: protein coding

About Slc9a4

Summary

Predicted to enable potassium:proton antiporter activity and sodium:proton antiporter activity. Predicted to be involved in potassium ion transmembrane transport; regulation of intracellular pH; and sodium ion import across plasma membrane. Predicted to act upstream of or within epithelial cell development and gastric acid secretion. Predicted to be located in several cellular components, including apical plasma membrane; basolateral plasma membrane; and vacuolar membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Orthologous to human SLC9A4 (solute carrier family 9 member A4). [provided by Alliance of Genome Resources, Apr 2022]

Slc9a4 Products(1)

mRNA Protein Name
NM_001413317.1 NP_001400246.1 sodium/hydrogen exchanger 4 precursor
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables sodium:proton antiporter activity IDA
IDA: Inferred from direct assay
8944646 RGD
Cellular Component GO Annotation Evidence Reference Source
located in basolateral plasma membrane IDA
IDA: Inferred from direct assay
11553518 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sodium/hydrogen exchanger 4

NHE-4

Na(+)/H(+) exchanger 4

solute carrier family 9 (sodium/hydrogen exchanger), member 4

solute carrier family 9 member 4

solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc9a4 NCBI NCBI:389015