SLC9A4 - solute carrier family 9 member A4 Gene

Also Known as NHE4

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 389015

About SLC9A4

Cytogenetic location: 2q12.1 Genomic coordinates (GRCh38): 2:102,473,226-102,533,972 (from NCBI)

This gene has 2 transcripts (splice variants), 134 orthologues and 10 paralogues. Biased expression in stomach (RPKM 24.9) and kidney (RPKM 5.2).

Summary

Predicted to enable potassium:proton antiporter activity and sodium:proton antiporter activity. Predicted to be involved in potassium ion transmembrane transport; regulation of intracellular pH; and sodium ion import across plasma membrane. Predicted to act upstream of or within epithelial cell development and gastric acid secretion. Predicted to be located in several cellular components, including apical plasma membrane; basolateral plasma membrane; and vacuolar membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

SLC9A4 Products (1)

mRNA Protein Name
NM_001011552.4 NP_001011552.2 sodium/hydrogen exchanger 4 precursor

SLC9A4 Protein Structure

Na_H_Exchanger

Na_H_Exchanger: Sodium/hydrogen exchanger family (74 - 476)

  • 0
  • 200
  • 400
  • 600
  • 798 a.a.
Protein Preferred Names Protein Names

sodium/hydrogen exchanger 4

  • NHE-4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13344 SLC9A4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus SLC9A4 VGNC VGNC:34943
Mus musculus SLC9A4 MGD MGI:105074
Felis catus SLC9A4 VGNC VGNC:65435
Macaca mulatta SLC9A4 VGNC VGNC:77641
Rattus norvegicus SLC9A4 RGD RGD:3721
Canis familiaris SLC9A4 VGNC VGNC:108217
Others SLC9A4 NCBI