1. Gene
  2. Arsb - arylsulfatase B Gene

Arsb - arylsulfatase B Gene

Rattus norvegicus
Gene ID: 25227 | Gene type: protein coding

About Arsb

Summary

Enables sulfuric ester hydrolase activity. Involved in several processes, including positive regulation of neuron projection development; response to estrogen; and response to methylmercury. Located in several cellular components, including Golgi apparatus; lysosome; and rough endoplasmic reticulum. Used to study mucopolysaccharidosis VI. Human ortholog(s) of this gene implicated in mucopolysaccharidosis VI. Orthologous to human ARSB (arylsulfatase B). [provided by Alliance of Genome Resources, Apr 2022]

Arsb Products(1)

mRNA Protein Name
NM_033443.1 NP_254278.1 arylsulfatase B precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables sulfuric ester hydrolase activity IDA
IDA: Inferred from direct assay
2884099 RGD
Biological Process GO Annotation Evidence Reference Source
involved in autophagy IDA
IDA: Inferred from direct assay
8037 RGD
involved in positive regulation of neuron projection development IMP
IMP: Inferred from mutant phenotype
24311516 RGD
involved in response to estrogen IDA
IDA: Inferred from direct assay
15040 RGD
involved in response to methylmercury IDA
IDA: Inferred from direct assay
1682910 RGD
involved in response to nutrient IDA
IDA: Inferred from direct assay
2290353 RGD
involved in response to pH IDA
IDA: Inferred from direct assay
6137211 RGD
Cellular Component GO Annotation Evidence Reference Source
located in cell surface IDA
IDA: Inferred from direct assay
19536613 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

arylsulfatase B

ASB

Arylsulfatase B (MPS VI)

G4S

N-acetylgalactosamine-4-sulfatase

Orthologs Information

Species Symbol Source ID
Homo sapiens Arsb NCBI NCBI:411