Tspear - thrombospondin type laminin G domain and EAR repeats Gene

Also Known as ORF65; Tnep1; TSP-EAR; C330046G03Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 252974

Summary

Acts upstream of or within Notch signaling pathway and hair cycle process. Located in cell surface; ciliary membrane; and stereocilium. Is expressed in several structures, including genitourinary system; gut; nervous system; sensory organ; and tooth. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 98 and ectodermal dysplasia 14. Orthologous to human TSPEAR (thrombospondin type laminin G domain and EAR repeats). [provided by Alliance of Genome Resources, Apr 2022]

Tspear Products (1)

mRNA Protein Name
NM_001287074.1 NP_001274003.1 thrombospondin-type laminin G domain and EAR repeat-containing protein precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within Notch signaling pathway IMP
IMP: Inferred from mutant phenotype
27736875 MGI
acts upstream of or within hair cycle process IMP
IMP: Inferred from mutant phenotype
27736875 MGI
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
22678063 MGI
located in ciliary membrane IDA
IDA: Inferred from direct assay
22678063 MGI
located in stereocilium IDA
IDA: Inferred from direct assay
22678063 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

thrombospondin-type laminin G domain and EAR repeat-containing protein

  • thrombospondin N-terminal domain/EPTP protein 1

  • thrombospondin-type laminin G domain and EAR repeats protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15176 TSPEAR Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tspear NCBI NCBI:54084