Myo1e - myosin IE Gene

Also Known as MYR5; Myr3

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25484

Summary

Predicted to enable several functions, including actin filament binding activity; Calmodulin binding activity; and microfilament motor activity. Predicted to be involved in several processes, including glomerular filtration; glomerulus development; and vesicle transport along actin filament. Predicted to act upstream of or within several processes, including platelet-derived growth factor receptor signaling pathway; post-embryonic hemopoiesis; and vasculogenesis. Located in cuticular plate. Part of protein-containing complex. Human ortholog(s) of this gene implicated in focal segmental glomerulosclerosis 6. Orthologous to human MYO1E (Myosin IE). [provided by Alliance of Genome Resources, Apr 2022]

Myo1e Products (1)

mRNA Protein Name
NM_173101.2 NP_775124.1 unconventional myosin-Ie

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Références Source
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
17257598 RGD
Cellular Component GO Annotation Evidence Références Source
located in cuticular plate IDA
IDA: Inferred from direct assay
12486594 RGD
part of protein-containing complex IDA
IDA: Inferred from direct assay
17257598 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

unconventional myosin-Ie

  • Unconventional myosin from rat 5

  • myosin heavy chain myr 3

  • myosin-Ie

  • unconventional myosin 1E

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS08941 MYO1E Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21659 Myo1c Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Myo1e NCBI NCBI:4643