2. Gene
  3. Kcnj6 - potassium inwardly-rectifying channel, subfamily J, member 6 Gene

Kcnj6 - potassium inwardly-rectifying channel, subfamily J, member 6 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 25743 | Gene type: protein coding

About Kcnj6

Summary

Enables G-protein alpha-subunit binding activity. Involved in cellular response to morphine and response to electrical stimulus. Located in several cellular components, including cell surface; dendrite; and neuronal cell body membrane. Human ortholog(s) of this gene implicated in alcohol use disorder and heroin dependence. Orthologous to human KCNJ6 (potassium inwardly rectifying channel subfamily J member 6). [provided by Alliance of Genome Resources, Apr 2022]

Kcnj6 Products(2)

mRNA Protein Name
NM_001393803.1 NP_001380732.1 G protein-activated inward rectifier potassium channel 2 isoform 2
NM_013192.3 NP_037324.1 G protein-activated inward rectifier potassium channel 2 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables G-protein alpha-subunit binding IDA
IDA: Inferred from direct assay
15731196 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
17828261 RGD
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to morphine IEP
IEP: Inferred from expression pattern
18178009 RGD
involved in response to electrical stimulus IEP
IEP: Inferred from expression pattern
10215164 RGD
Cellular Component GO Annotation Evidence Reference Source
located in axon IDA
IDA: Inferred from direct assay
15305864 RGD
located in cell surface IDA
IDA: Inferred from direct assay
19118198 RGD
located in dendrite IDA
IDA: Inferred from direct assay
19118198 RGD
located in neuronal cell body membrane IDA
IDA: Inferred from direct assay
15305864 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

G protein-activated inward rectifier potassium channel 2

BIR1

GIRK-2

GIRK2

KATP-2

inward rectifier K(+) channel Kir3.2

potassium channel, inwardly rectifying subfamily J member 6

potassium voltage-gated channel subfamily J member 6

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07149 KCNJ6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kcnj6 NCBI NCBI:3763