TRIM58 - tripartite motif containing 58 Gene

Also Known as BIA2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 25893

About TRIM58

This gene has 1 transcript (splice variant), 92 orthologues and 80 paralogues. Biased expression in bone marrow (RPKM 12.4), thyroid (RPKM 11.2) and 5 other tissues.

Summary

Predicted to enable dynein heavy chain binding activity; dynein intermediate chain binding activity; and ubiquitin protein Ligase activity. Predicted to be involved in several processes, including positive regulation of erythrocyte enucleation; protein ubiquitination; and regulation of nuclear migration along microtubule. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

TRIM58 Products (1)

mRNA Protein Name
NM_015431.4 NP_056246.3 E3 ubiquitin-protein ligase TRIM58

TRIM58 Protein Structure

zf-C3HC4_4

zf-C3HC4_4: zinc finger of C3HC4-type, RING (16 - 60)

zf-B_box

zf-B_box: B-box zinc finger (93 - 132)

PRY

PRY: SPRY-associated domain (293 - 341)

SPRY

SPRY: SPRY domain (343 - 450)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 486 a.a.
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase TRIM58

  • RING-type E3 ubiquitin transferase TRIM58

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15058 TRIM58 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus TRIM58 MGD MGI:2684862
Canis familiaris TRIM58 VGNC VGNC:47828
Macaca mulatta TRIM58 VGNC VGNC:100177
Rattus norvegicus TRIM58 RGD RGD:1566174
Bos taurus TRIM58 VGNC VGNC:36343
Felis catus TRIM58 VGNC VGNC:66546
Others TRIM58 NCBI