KRT23 - keratin 23 Gene

Also Known as K23; CK23; HAIK1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 25984

About KRT23

Cytogenetic location: 17q21.2 Genomic coordinates (GRCh38): 17:40,922,700-40,937,646 (from NCBI)

This gene has 9 transcripts (splice variants), 1 gene allele, 119 orthologues and 68 paralogues. Biased expression in placenta (RPKM 45.8), skin (RPKM 39.5) and 7 other tissues.

Summary

The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

KRT23 Products (2)

mRNA Protein Name
NM_001282433.2 NP_001269362.1 keratin, type I cytoskeletal 23 isoform 2
NM_015515.5 NP_056330.3 keratin, type I cytoskeletal 23 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

KRT23 Protein Structure

Filament

Filament: Intermediate filament protein (71 - 380)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 422 a.a.
Protein Preferred Names Protein Names

keratin, type I cytoskeletal 23

  • CK-23

KRT23 Antibodies

Cat. No. Product Name Application Reactivity
HY-P89785 Cytokeratin 23 Antibody (YA9129) WB, ICC/IF, IF-Tissue, IHC-P, IP, ELISA human

Related Diseases

Diseases Alias
Transitional Papilloma

  • Transitional Cell Papilloma

  • Transitional Cell Papilloma, Benign
Van Den Ende-Gupta Syndrome

  • VDEGS

  • Blepharophimosis, Arachnodactyly, And Congenital Contractures

  • Marden-Walker-Like Syndrome

  • Marden-Walker-Like Syndrome Without Psychomotor Retardation

  • Marden Walker Like Syndrome

  • Marden-Walker-Like Syndrome Without Psychmotor Retardation

  • Van Den Ende Gupta Syndrome

  • Marden Walker Like Syndrome Without Psychomotor Retardation

  • Blepharophimosis Arachnodactyly And Congenital Contractures
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07447 KRT23 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta KRT23 VGNC VGNC:74211
Canis familiaris KRT23 VGNC VGNC:42522
Rattus norvegicus KRT23 RGD RGD:1308838
Felis catus KRT23 VGNC VGNC:67987
Mus musculus KRT23 MGD MGI:2148866
Bos taurus KRT23 VGNC VGNC:30722
Others KRT23 NCBI