mt-Nd6 - NADH dehydrogenase 6, mitochondrial Gene

Also Known as ND6

Species: Rattus norvegicus (strain: BN/SsNHsdMCW)

Gene Type: protein coding
Gene ID: 26203

Summary

Predicted to enable NADH dehydrogenase (ubiquinone) activity. Involved in response to cocaine; response to hydrogen peroxide; and response to nicotine. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in Leber hereditary optic neuropathy; Leigh disease; and spinal muscular atrophy with lower extremity predominante 2B. Orthologous to human MT-ND6 (mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6). [provided by Alliance of Genome Resources, Apr 2022]

mt-Nd6 Products (2)

mRNA Protein Name
YP_665640.1 NADH dehydrogenase subunit 6 (mitochondrion) [Rattus norvegicus]
YP_665640.1 NADH dehydrogenase subunit 6 (mitochondrion) [Rattus norvegicus]

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in response to cocaine IEP
IEP: Inferred from expression pattern
9261805 RGD
involved in response to hydrogen peroxide IEP
IEP: Inferred from expression pattern
9788897 RGD
involved in response to nicotine IEP
IEP: Inferred from expression pattern
19460297 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

  • NADH dehydrogenase subunit 6

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08802 MT-ND6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens mt-Nd6 NCBI NCBI:4541