KCNG2 - potassium voltage-gated channel modifier subfamily G member 2 Gene

Homo sapiens

Also known as KCNF2; KV6.2

Gene ID: 26251 | Gene type: protein coding

About KCNG2

Cytogenetic location: 18q23 Genomic coordinates (GRCh38): 18:79,797,938-79,900,100 (from NCBI)

This gene has 2 transcripts (splice variants), 184 orthologues and 31 paralogues. Low expression observed in reference dataset.

Summary

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, Insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the Potassium Channel, voltage-gated, subfamily G. This member is a gamma subunit of the voltage-gated Potassium Channel. The delayed-rectifier type channels containing this subunit may contribute to cardiac action potential repolarization. [provided by RefSeq, Jul 2008]

KCNG2 Products(1)

mRNA	Protein	Name
NM_012283.2	NP_036415.1	potassium voltage-gated channel subfamily G member 2

KCNG2 Protein Structure

BTB_2

Ion_trans

0
100
200
300
400
466 a.a.

Protein Preferred Names

Protein Names

potassium voltage-gated channel subfamily G member 2

cardiac potassium channel subunit

Related Diseases

Diseases

Alias

Sick Sinus Syndrome

Sinus Node Dysfunction	Sinus Node Disease
Sinus Node Infection	Snd
Sss	Snd - [Sinus Node Dysfunction]
Sinoatrial Node Dysfunction	Sss - [Sick Sinus Syndrome]
Sick Sinus	Sick Sinus Tachycardia

Pyromania

Firesetting Behavior	Pathological Firesetting
Pathological Fire-Setting

Opioid Abuse

Opioid-Related Disorders

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07122	KCNG2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	KCNG2	VGNC	VGNC:30443
Mus musculus	KCNG2	MGD	MGI:3694646
Macaca mulatta	KCNG2	VGNC	VGNC:104227
Felis catus	KCNG2	VGNC	VGNC:107711
Rattus norvegicus	KCNG2	RGD	RGD:1309521

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