Spata2 - spermatogenesis associated 2 Gene

Also Known as mKIAA0757

Species: Mus musculus

Gene Type: protein coding
Gene ID: 263876

Summary

Predicted to enable signaling receptor complex adaptor activity and Ubiquitin-Specific Protease binding activity. Involved in protein linear deubiquitination; regulation of necroptotic process; and regulation of tumor necrosis factor-mediated signaling pathway. Acts upstream of or within seminiferous tubule development and spermatogenesis. Located in cytoplasm. Is expressed in several structures, including alimentary system; eye; genitourinary system; nervous system; and respiratory system. Orthologous to human SPATA2 (spermatogenesis associated 2). [provided by Alliance of Genome Resources, Apr 2022]

Spata2 Products (12)

mRNA Protein Name
NM_001356523.2 NP_001343452.1 spermatogenesis-associated protein 2 isoform 2
NM_001411393.1 NP_001398322.1 spermatogenesis-associated protein 2 isoform 1
NM_001411394.1 NP_001398323.1 spermatogenesis-associated protein 2 isoform 1
NM_001411395.1 NP_001398324.1 spermatogenesis-associated protein 2 isoform 1
NM_001411396.1 NP_001398325.1 spermatogenesis-associated protein 2 isoform 1
NM_001411397.1 NP_001398326.1 spermatogenesis-associated protein 2 isoform 1
NM_001411398.1 NP_001398327.1 spermatogenesis-associated protein 2 isoform 1
NM_001411416.1 NP_001398345.1 spermatogenesis-associated protein 2 isoform 3
NM_001411417.1 NP_001398346.1 spermatogenesis-associated protein 2 isoform 4
NM_001411418.1 NP_001398347.1 spermatogenesis-associated protein 2 isoform 4
NM_001411419.1 NP_001398348.1 spermatogenesis-associated protein 2 isoform 4
NM_170756.3 NP_739562.1 spermatogenesis-associated protein 2 isoform 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of necroptotic process IMP
IMP: Inferred from mutant phenotype
27545878 MGI
involved in protein linear deubiquitination IMP
IMP: Inferred from mutant phenotype
28701375 MGI
involved in regulation of necroptotic process IMP
IMP: Inferred from mutant phenotype
28701375 MGI
involved in regulation of tumor necrosis factor-mediated signaling pathway IMP
IMP: Inferred from mutant phenotype
28701375 MGI
acts upstream of or within seminiferous tubule development IMP
IMP: Inferred from mutant phenotype
29025062 MGI
acts upstream of or within spermatogenesis IMP
IMP: Inferred from mutant phenotype
29025062 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
29025062 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

spermatogenesis-associated protein 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13639 SPATA2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Spata2 NCBI NCBI:9825