Sclt1 - sodium channel and clathrin linker 1 Gene

Rattus norvegicus

Also known as Sap1; CAP-1A

Gene ID: 266809 | Gene type: protein coding

About Sclt1

Summary

Enables clathrin binding activity; protein C-terminus binding activity; and Sodium Channel regulator activity. Involved in clustering of voltage-gated sodium channels. Part of clathrin complex. Orthologous to human SCLT1 (Sodium Channel and clathrin linker 1). [provided by Alliance of Genome Resources, Apr 2022]

Sclt1 Products(1)

mRNA	Protein	Name
NM_153740.1	NP_714962.1	sodium channel and clathrin linker 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables clathrin binding	IDA IDA: Inferred from direct assay	15797711	RGD
enables protein binding	IPI IPI: Inferred from physical interaction	15797711	RGD
enables sodium channel regulator activity	IMP IMP: Inferred from mutant phenotype	15797711	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in clustering of voltage-gated sodium channels	IMP IMP: Inferred from mutant phenotype	15797711	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
part of clathrin complex	IDA IDA: Inferred from direct assay	15797711	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

sodium channel and clathrin linker 1

clathrin-associated protein 1A	sodium channel Nav1.8-binding protein
sodium channel-associated protein 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12513	SCLT1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Sclt1	NCBI	NCBI:132320

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