Kcnc2 - potassium voltage gated channel, Shaw-related subfamily, member 2 Gene

Also Known as Kv3.2; KShIIIA; B230117I07

Species: Mus musculus

Gene Type: protein coding
Gene ID: 268345

Summary

Enables transmembrane transporter binding activity. Acts upstream of or within action potential. Located in several cellular components, including neuronal cell body membrane; perikaryon; and synaptic membrane. Is expressed in eye; genitourinary system; gut; heart; and nervous system. Orthologous to human KCNC2 (potassium voltage-gated channel subfamily C member 2). [provided by Alliance of Genome Resources, Apr 2022]

Kcnc2 Products (5)

mRNA Protein Name
NM_001025581.1 NP_001020752.1 potassium voltage-gated channel subfamily C member 2 isoform 2
NM_001359752.1 NP_001346681.1 potassium voltage-gated channel subfamily C member 2 isoform 1
NM_001359753.1 NP_001346682.1 potassium voltage-gated channel subfamily C member 2 isoform 1
NM_001379643.1 NP_001366572.1 potassium voltage-gated channel subfamily C member 2 isoform 1
NM_001379644.1 NP_001366573.1 potassium voltage-gated channel subfamily C member 2 isoform 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
10531438 MGI
enables transmembrane transporter binding IPI
IPI: Inferred from physical interaction
12000114 MGI
enables voltage-gated potassium channel activity IDA
IDA: Inferred from direct assay
10561420 MGI
enables voltage-gated potassium channel activity IMP
IMP: Inferred from mutant phenotype
10903572 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within action potential IMP
IMP: Inferred from mutant phenotype
17761775 MGI
involved in membrane hyperpolarization IMP
IMP: Inferred from mutant phenotype
17761775 MGI
involved in potassium ion transport IDA
IDA: Inferred from direct assay
10561420 MGI
involved in potassium ion transport IMP
IMP: Inferred from mutant phenotype
11124984 MGI
involved in regulation of action potential firing rate IMP
IMP: Inferred from mutant phenotype
10561420 MGI
Cellular Component GO Annotation Evidence References Source
located in axon IDA
IDA: Inferred from direct assay
10903572 MGI
located in cell body IDA
IDA: Inferred from direct assay
15317859 MGI
located in dendrite IDA
IDA: Inferred from direct assay
10531438 MGI
located in membrane IDA
IDA: Inferred from direct assay
12000114 MGI
located in neuronal cell body membrane IDA
IDA: Inferred from direct assay
10531438 MGI
located in perikaryon IDA
IDA: Inferred from direct assay
10531438 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
15317859 MGI
located in postsynaptic membrane IDA
IDA: Inferred from direct assay
10531438 MGI
located in presynaptic membrane IDA
IDA: Inferred from direct assay
10531438 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

potassium voltage-gated channel subfamily C member 2

  • shaw-like potassium channel

  • voltage-gated potassium channel Kv3.2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07109 KCNC2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kcnc2 NCBI NCBI:3747