Cntrl - centriolin Gene

Also Known as Cep1; IB3/5; Ma2a8; Cep110; b2b1468Clo; b2b1468.1Clo; 6720467O09Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 26920

Summary

Predicted to enable cytoskeletal protein binding activity. Acts upstream of or within circulatory system development; female germ-line stem cell asymmetric division; and kidney development. Located in meiotic spindle pole; mitotic spindle pole; and perinuclear region of cytoplasm. Is expressed in midbrain ventricular layer and telencephalon ventricular layer. Used to study nephronophthisis. Orthologous to human CNTRL (centriolin). [provided by Alliance of Genome Resources, Apr 2022]

Cntrl Products (4)

mRNA Protein Name
NM_001290635.1 NP_001277564.1 centriolin isoform 3
NM_001379274.1 NP_001366203.1 centriolin isoform 4
NM_001379275.1 NP_001366204.1 centriolin isoform 5
NM_012018.2 NP_036148.2 centriolin isoform 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within aorta development IMP
IMP: Inferred from mutant phenotype
25807483 MGI
acts upstream of or within cardiac septum development IMP
IMP: Inferred from mutant phenotype
25807483 MGI
acts upstream of or within coronary vasculature development IMP
IMP: Inferred from mutant phenotype
25807483 MGI
acts upstream of or within female germ-line stem cell asymmetric division IMP
IMP: Inferred from mutant phenotype
28075662 MGI
acts upstream of or within kidney development IMP
IMP: Inferred from mutant phenotype
27002738 MGI
acts upstream of or within ventricular septum development IMP
IMP: Inferred from mutant phenotype
25807483 MGI
Cellular Component GO Annotation Evidence References Source
located in meiotic spindle IDA
IDA: Inferred from direct assay
28075662 MGI
located in meiotic spindle pole IDA
IDA: Inferred from direct assay
28075662 MGI
located in mitotic spindle pole IDA
IDA: Inferred from direct assay
25220058 MGI
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
8982254 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

centriolin

  • 110 kDa centrosomal protein

  • antigen identified by monoclonal antibody 2A8

  • centrosomal protein 110

  • centrosomal protein of 110 kDa

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02938 CNTRL Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cntrl NCBI NCBI:11064