2. Gene
  3. Cntrl - centriolin Gene

Cntrl - centriolin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Cep1; IB3/5; Ma2a8; Cep110; b2b1468Clo; b2b1468.1Clo; 6720467O09Rik

Gene ID: 26920 | Gene type: protein coding

About Cntrl

Summary

Predicted to enable cytoskeletal protein binding activity. Acts upstream of or within circulatory system development; female germ-line stem cell asymmetric division; and kidney development. Located in meiotic spindle pole; mitotic spindle pole; and perinuclear region of cytoplasm. Is expressed in midbrain ventricular layer and telencephalon ventricular layer. Used to study nephronophthisis. Orthologous to human CNTRL (centriolin). [provided by Alliance of Genome Resources, Apr 2022]

Cntrl Products(4)

mRNA Protein Name
NM_001290635.1 NP_001277564.1 centriolin isoform 3
NM_001379274.1 NP_001366203.1 centriolin isoform 4
NM_001379275.1 NP_001366204.1 centriolin isoform 5
NM_012018.2 NP_036148.2 centriolin isoform 1
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within aorta development IMP
IMP: Inferred from mutant phenotype
25807483 MGI
acts upstream of or within cardiac septum development IMP
IMP: Inferred from mutant phenotype
25807483 MGI
acts upstream of or within coronary vasculature development IMP
IMP: Inferred from mutant phenotype
25807483 MGI
acts upstream of or within female germ-line stem cell asymmetric division IMP
IMP: Inferred from mutant phenotype
28075662 MGI
acts upstream of or within kidney development IMP
IMP: Inferred from mutant phenotype
27002738 MGI
acts upstream of or within ventricular septum development IMP
IMP: Inferred from mutant phenotype
25807483 MGI
Cellular Component GO Annotation Evidence Reference Source
located in meiotic spindle IDA
IDA: Inferred from direct assay
28075662 MGI
located in meiotic spindle pole IDA
IDA: Inferred from direct assay
28075662 MGI
located in mitotic spindle pole IDA
IDA: Inferred from direct assay
25220058 MGI
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
8982254 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

centriolin

110 kDa centrosomal protein

antigen identified by monoclonal antibody 2A8

centrosomal protein 110

centrosomal protein of 110 kDa

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02938 CNTRL Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cntrl NCBI NCBI:11064