Pla2g2f - phospholipase A2, group IIF Gene

Also Known as GIIFsPLA2; sPLA2-IIF

Species: Mus musculus

Gene Type: protein coding
Gene ID: 26971

Summary

Enables Phospholipase A2 activity. Involved in arachidonic acid metabolic process and phosphatidylethanolamine acyl-chain remodeling. Acts upstream of or within negative regulation of T cell proliferation and phospholipid metabolic process. Predicted to be located in extracellular region and plasma membrane. Is expressed in several structures, including alimentary system; integumental system; nervous system; sensory organ; and urinary system. Orthologous to human PLA2G2F (Phospholipase A2 group IIF). [provided by Alliance of Genome Resources, Apr 2022]

Pla2g2f Products (2)

mRNA Protein Name
NM_001360875.1 NP_001347804.1 group IIF secretory phospholipase A2 isoform 2 precursor
NM_012045.4 NP_036175.2 group IIF secretory phospholipase A2 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables phospholipase A2 activity IDA
IDA: Inferred from direct assay
16931517 MGI
Biological Process GO Annotation Evidence References Source
involved in arachidonate metabolic process IMP
IMP: Inferred from mutant phenotype
11877435 MGI
acts upstream of or within negative regulation of T cell proliferation IDA
IDA: Inferred from direct assay
16931517 MGI
involved in phosphatidylethanolamine acyl-chain remodeling IDA
IDA: Inferred from direct assay
11877435 MGI
acts upstream of or within phospholipid metabolic process IDA
IDA: Inferred from direct assay
16931517 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

group IIF secretory phospholipase A2

  • GIIF sPLA2

  • phosphatidylcholine 2-acylhydrolase 2F

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10624 PLA2G2F Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pla2g2f NCBI NCBI:64600