PLA2G2F - phospholipase A2 group IIF Gene

Also Known as GIIFsPLA2; sPLA2-IIF

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 64600

About PLA2G2F

Cytogenetic location: 1p36.12 Genomic coordinates (GRCh38): 1:20,139,323-20,150,381 (from NCBI)

This gene has 2 transcripts (splice variants), 115 orthologues and 8 paralogues. Biased expression in skin (RPKM 4.4), urinary bladder (RPKM 2.2) and 1 other tissue.

Summary

Enables calcium-dependent Phospholipase A2 activity. Involved in glycerophospholipid metabolic process. Predicted to be located in cytosol and extracellular region. [provided by Alliance of Genome Resources, Apr 2022]

PLA2G2F Products (2)

mRNA Protein Name
NM_001360869.2 NP_001347798.1 group IIF secretory phospholipase A2 isoform 2 precursor
NM_022819.4 NP_073730.3 group IIF secretory phospholipase A2 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables calcium-dependent phospholipase A2 activity IDA
IDA: Inferred from direct assay
11112443 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Biological Process GO Annotation Evidence References Source
involved in phosphatidylcholine acyl-chain remodeling IDA
IDA: Inferred from direct assay
11112443 GOA
involved in phosphatidylethanolamine acyl-chain remodeling IDA
IDA: Inferred from direct assay
11112443 GOA
involved in phosphatidylglycerol acyl-chain remodeling IDA
IDA: Inferred from direct assay
11112443 GOA
involved in phosphatidylserine acyl-chain remodeling IDA
IDA: Inferred from direct assay
11112443 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PLA2G2F Protein Structure

Phospholip_A2_1

Phospholip_A2_1: Phospholipase A2 (65 - 174)

  • 0
  • 100
  • 200
  • 211 a.a.
Protein Preferred Names Protein Names

group IIF secretory phospholipase A2

  • GIIF sPLA2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10624 PLA2G2F Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus PLA2G2F RGD RGD:1597305
Bos taurus PLA2G2F VGNC VGNC:32958
Canis familiaris PLA2G2F VGNC VGNC:44624
Mus musculus PLA2G2F MGD MGI:1349661
Felis catus PLA2G2F VGNC VGNC:80305
Others PLA2G2F NCBI