Lhfpl4 - lipoma HMGIC fusion partner-like protein 4 Gene

Also Known as mKIAA4027; B230384L07; 1190004M23Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 269788

Summary

Enables GABA Receptor binding activity. Involved in gamma-aminobutyric acid receptor clustering and regulation of inhibitory synapse assembly. Located in inhibitory synapse and postsynaptic membrane. Is expressed in brain; heart; intestine; lung; and reproductive system. Orthologous to human LHFPL4 (LHFPL tetraspan subfamily member 4). [provided by Alliance of Genome Resources, Apr 2022]

Lhfpl4 Products (1)

mRNA Protein Name
NM_177763.3 NP_808431.2 LHFPL tetraspan subfamily member 4 protein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables GABA receptor binding IDA
IDA: Inferred from direct assay
28978485 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
28978485 MGI
Biological Process GO Annotation Evidence References Source
involved in gamma-aminobutyric acid receptor clustering IMP
IMP: Inferred from mutant phenotype
28279354 MGI
involved in neurotransmitter receptor localization to postsynaptic specialization membrane IDA
IDA: Inferred from direct assay
28279354 MGI
involved in neurotransmitter receptor localization to postsynaptic specialization membrane IMP
IMP: Inferred from mutant phenotype
28279354 MGI
involved in regulation of inhibitory synapse assembly IMP
IMP: Inferred from mutant phenotype
29742426 MGI
Cellular Component GO Annotation Evidence References Source
is active in GABA-ergic synapse IDA
IDA: Inferred from direct assay
28279354 MGI
is active in GABA-ergic synapse IEP
IEP: Inferred from expression pattern
28279354 MGI
is active in GABA-ergic synapse IMP
IMP: Inferred from mutant phenotype
28279354 MGI
located in inhibitory synapse IDA
IDA: Inferred from direct assay
29742426 MGI
located in postsynaptic membrane IDA
IDA: Inferred from direct assay
28978485 MGI
located in postsynaptic membrane IMP
IMP: Inferred from mutant phenotype
29742426 MGI
is active in postsynaptic specialization IDA
IDA: Inferred from direct assay
28279354 MGI
is active in postsynaptic specialization IEP
IEP: Inferred from expression pattern
28279354 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

LHFPL tetraspan subfamily member 4 protein

  • GABAA receptor regulatory Lhfpl4

  • lipoma HMGIC fusion partner-like 4 protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07627 LHFPL3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07628 LHFPL4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lhfpl4 NCBI NCBI:375323