Npas3 - neuronal PAS domain protein 3 Gene

Also Known as bHLHe12; 4930423H22Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 27386

Summary

Enables protein heterodimerization activity. Involved in positive regulation of transcription, DNA-templated. Acts upstream of or within locomotory behavior; maternal behavior; and startle response. Located in nucleus. Is expressed in several structures, including central nervous system; heart and pericardium; salivary gland; sensory organ; and urinary system. Orthologous to human NPAS3 (neuronal PAS domain protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Npas3 Products (6)

mRNA Protein Name
NM_001370960.1 NP_001357889.1 neuronal PAS domain-containing protein 3 isoform 2
NM_001370961.1 NP_001357890.1 neuronal PAS domain-containing protein 3 isoform 3
NM_001370962.1 NP_001357891.1 neuronal PAS domain-containing protein 3 isoform 4
NM_001370963.1 NP_001357892.1 neuronal PAS domain-containing protein 3 isoform 5
NM_001370964.1 NP_001357893.1 neuronal PAS domain-containing protein 3 isoform 6
NM_013780.3 NP_038808.3 neuronal PAS domain-containing protein 3 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
7743923 MGI
enables protein heterodimerization activity IDA
IDA: Inferred from direct assay
27782878 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within locomotory behavior IMP
IMP: Inferred from mutant phenotype
15347806 MGI
acts upstream of or within maternal behavior IGI
IGI: Inferred from genetic interaction
15347806 MGI
involved in positive regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
7743923 MGI
acts upstream of or within startle response IGI
IGI: Inferred from genetic interaction
15347806 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
15347806 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

neuronal PAS domain-containing protein 3

  • basic-helix-loop-helix-PAS protein MOP6

  • member of PAS protein 6

  • neuronal PAS3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-112374 NPAS3-IN-1 Inhibitor 98.72% Unkown
HY-RS09470 NPAS3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Npas3 NCBI NCBI:64067