C2cd3 - C2 calcium-dependent domain containing 3 Gene

Mus musculus

Gene ID: 277939 | Gene type: protein coding

About C2cd3

Summary

Involved in centriole elongation. Acts upstream of or within several processes, including chordate embryonic development; embryonic morphogenesis; and protein localization to centrosome. Located in centriolar satellite; centriole; and ciliary basal body. Is expressed in early conceptus and secondary oocyte. Human ortholog(s) of this gene implicated in orofaciodigital syndrome. Orthologous to human C2CD3 (C2 domain containing 3 centriole elongation regulator). [provided by Alliance of Genome Resources, Apr 2022]

C2cd3 Products(1)

mRNA	Protein	Name
NM_001017985.3	NP_001017985.2	C2 domain-containing protein 3

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	24469809	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within brain development	IMP IMP: Inferred from mutant phenotype	19004860	MGI
involved in centriole elongation	IDA IDA: Inferred from direct assay	24997988	MGI
acts upstream of or within cilium assembly	IMP IMP: Inferred from mutant phenotype	19004860	MGI
acts upstream of or within embryonic digit morphogenesis	IMP IMP: Inferred from mutant phenotype	19004860	MGI
acts upstream of or within embryonic limb morphogenesis	IMP IMP: Inferred from mutant phenotype	19004860	MGI
acts upstream of or within heart looping	IMP IMP: Inferred from mutant phenotype	19004860	MGI
acts upstream of or within in utero embryonic development	IMP IMP: Inferred from mutant phenotype	19004860	MGI
acts upstream of or within neural plate axis specification	IMP IMP: Inferred from mutant phenotype	19004860	MGI
acts upstream of or within neural tube development	IMP IMP: Inferred from mutant phenotype	19004860	MGI
acts upstream of or within pattern specification process	IMP IMP: Inferred from mutant phenotype	19004860	MGI
acts upstream of or within protein localization to centrosome	IMP IMP: Inferred from mutant phenotype	24469809	MGI
acts upstream of or within protein processing	IMP IMP: Inferred from mutant phenotype	19004860	MGI
acts upstream of or within regulation of proteolysis	IDA IDA: Inferred from direct assay	19004860	MGI
acts upstream of or within regulation of smoothened signaling pathway	IGI IGI: Inferred from genetic interaction	19004860	MGI
acts upstream of or within regulation of smoothened signaling pathway	IMP IMP: Inferred from mutant phenotype	19004860	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in centriolar satellite	IDA IDA: Inferred from direct assay	24469809	MGI
located in centriole	IDA IDA: Inferred from direct assay	24469809	MGI
located in ciliary basal body	IDA IDA: Inferred from direct assay	19004860	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

C2 domain-containing protein 3

protein hearty

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01740	C2CD3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	C2cd3	NCBI	NCBI:26005

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