C2cd3 - C2 calcium-dependent domain containing 3 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 277939

Summary

Involved in centriole elongation. Acts upstream of or within several processes, including chordate embryonic development; embryonic morphogenesis; and protein localization to centrosome. Located in centriolar satellite; centriole; and ciliary basal body. Is expressed in early conceptus and secondary oocyte. Human ortholog(s) of this gene implicated in orofaciodigital syndrome. Orthologous to human C2CD3 (C2 domain containing 3 centriole elongation regulator). [provided by Alliance of Genome Resources, Apr 2022]

C2cd3 Products (1)

mRNA Protein Name
NM_001017985.3 NP_001017985.2 C2 domain-containing protein 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
24469809 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within brain development IMP
IMP: Inferred from mutant phenotype
19004860 MGI
involved in centriole elongation IDA
IDA: Inferred from direct assay
24997988 MGI
acts upstream of or within cilium assembly IMP
IMP: Inferred from mutant phenotype
19004860 MGI
acts upstream of or within embryonic digit morphogenesis IMP
IMP: Inferred from mutant phenotype
19004860 MGI
acts upstream of or within embryonic limb morphogenesis IMP
IMP: Inferred from mutant phenotype
19004860 MGI
acts upstream of or within heart looping IMP
IMP: Inferred from mutant phenotype
19004860 MGI
acts upstream of or within in utero embryonic development IMP
IMP: Inferred from mutant phenotype
19004860 MGI
acts upstream of or within neural plate axis specification IMP
IMP: Inferred from mutant phenotype
19004860 MGI
acts upstream of or within neural tube development IMP
IMP: Inferred from mutant phenotype
19004860 MGI
acts upstream of or within pattern specification process IMP
IMP: Inferred from mutant phenotype
19004860 MGI
acts upstream of or within protein localization to centrosome IMP
IMP: Inferred from mutant phenotype
24469809 MGI
acts upstream of or within protein processing IMP
IMP: Inferred from mutant phenotype
19004860 MGI
acts upstream of or within regulation of proteolysis IDA
IDA: Inferred from direct assay
19004860 MGI
acts upstream of or within regulation of smoothened signaling pathway IGI
IGI: Inferred from genetic interaction
19004860 MGI
acts upstream of or within regulation of smoothened signaling pathway IMP
IMP: Inferred from mutant phenotype
19004860 MGI
Cellular Component GO Annotation Evidence References Source
located in centriolar satellite IDA
IDA: Inferred from direct assay
24469809 MGI
located in centriole IDA
IDA: Inferred from direct assay
24469809 MGI
located in ciliary basal body IDA
IDA: Inferred from direct assay
19004860 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

C2 domain-containing protein 3

  • protein hearty

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01740 C2CD3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens C2cd3 NCBI NCBI:26005